Literature DB >> 11390920

The Neuroimmune Interface in Prion Diseases.

Michael A. Klein1, Adriano Aguzzi.   

Abstract

Prion diseases are fatal neurodegenerative disorders of animals and humans. Here we address the role of the immune system in the spread of prions from peripheral sites to the central nervous system and its potential relevance to iatrogenic prion disease.

Entities:  

Year:  2000        PMID: 11390920     DOI: 10.1152/physiologyonline.2000.15.5.250

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN: 0886-1714


  2 in total

1.  Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells.

Authors:  Alessandra Handisurya; Sabine Gilch; Dorian Winter; Saeed Shafti-Keramat; Dieter Maurer; Hermann M Schätzl; Reinhard Kirnbauer
Journal:  FEBS J       Date:  2007-02-20       Impact factor: 5.542

2.  Overexpression of PrPc, combined with MGr1-Ag/37LRP, is predictive of poor prognosis in gastric cancer.

Authors:  Lin Zhou; Yulong Shang; Changhao Liu; Jinge Li; Hao Hu; Cong Liang; Yanan Han; Wei Zhang; Jie Liang; Kaichun Wu
Journal:  Int J Cancer       Date:  2014-04-17       Impact factor: 7.396

  2 in total

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