| Literature DB >> 11390911 |
Thomas Kietzmann1, Joachim Fandrey, Helmut Acker.
Abstract
Changes in ambient PO(2) need to be sensed to allow long-term adaptation of cellular functions via the regulation of gene activity. The generation of OH* from H(2)O(2) in an iron-dependent perinuclear Fenton reaction for triggering gene expression could be the key event in the O(2) signaling pathway.Entities:
Year: 2000 PMID: 11390911 DOI: 10.1152/physiologyonline.2000.15.4.202
Source DB: PubMed Journal: News Physiol Sci ISSN: 0886-1714