Literature DB >> 11390858

P-450 Eicosanoids: A Novel Signaling Pathway Regulating Renal Function.

Richard J. Roman1, Magdalena Alonso-Galicia.   

Abstract

Cytochrome P-450 enzymes primarily metabolize arachidonic acid to epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE) in the kidney. These compounds serve as second messengers that play a central role in the regulation of renal vascular tone and sodium reabsorption in the proximal tubule and thick ascending loop of Henle.

Entities:  

Year:  1999        PMID： 11390858     DOI： 10.1152/physiologyonline.1999.14.6.238

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  9 in total

Review 1.  Cytochrome P450 and Lipoxygenase Metabolites on Renal Function.

Authors:  John D Imig; Md Abdul Hye Khan
Journal:  Compr Physiol       Date:  2015-12-15       Impact factor: 9.090

2.  Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats.

Authors:  Kathleen M Lukaszewicz; Matthew J Durand; Jessica R C Priestley; James R Schmidt; L Adrienne Allen; Aron M Geurts; Julian H Lombard
Journal:  J Vis Exp       Date:  2017-12-05       Impact factor: 1.355

Review 3.  Renal dopamine and sodium homeostasis.

Authors:  P A Jose; G M Eisner; R A Felder
Journal:  Curr Hypertens Rep       Date:  2000-04       Impact factor: 5.369

Review 4.  Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.

Authors:  Fan Fan; Ying Ge; Wenshan Lv; Matthew R Elliott; Yoshikazu Muroya; Takashi Hirata; George W Booz; Richard J Roman
Journal:  Front Biosci (Landmark Ed)       Date:  2016-06-01

5.  Epoxyeicosatrienoic acids affect electrolyte transport in renal tubular epithelial cells: dependence on cyclooxygenase and cell polarity.

Authors:  Rolf M Nüsing; Horst Schweer; Ingrid Fleming; Darryl C Zeldin; Markus Wegmann
Journal:  Am J Physiol Renal Physiol       Date:  2007-05-09

6.  Endogenously produced 20-HETE modulates myogenic and TGF response in microperfused afferent arterioles.

Authors:  Ying Ge; Sydney R Murphy; Yan Lu; John Falck; Ruisheng Liu; Richard J Roman
Journal:  Prostaglandins Other Lipid Mediat       Date:  2013-03-14       Impact factor: 3.072

Review 7.  The Physiopathology of Cardiorenal Syndrome: A Review of the Potential Contributions of Inflammation.

Authors:  John G Kingma; Denys Simard; Jacques R Rouleau; Benoit Drolet; Chantale Simard
Journal:  J Cardiovasc Dev Dis       Date:  2017-11-29

Review 8.  Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target.

Authors:  Osama H Elshenawy; Sherif M Shoieb; Anwar Mohamed; Ayman O S El-Kadi
Journal:  Pharmaceutics       Date:  2017-02-20       Impact factor: 6.321

9.  20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels.

Authors:  Fan Fan; Cheng-Wen Sun; Kristopher G Maier; Jan M Williams; Malikarjuna R Pabbidi; Sean P Didion; John R Falck; Jialong Zhuo; Richard J Roman
Journal:  PLoS One       Date:  2013-12-04       Impact factor: 3.240
  9 in total

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