Literature DB >> 11390824

A Unique Role of NO in the Control of Blood Flow.

Ulrich Pohl1, Cor de Wit.   

Abstract

Nitric oxide synthase (NOS) inhibitors induce significant vasoconstriction, suggesting an indispensable role of NO as a local vasodilator. This is due mainly to its effects on large arterioles that significantly control arterial conductance while scarcely being regulated by metabolites. NO's role in adapting vascular conductance to flow is pronounced during (re)active hyperemia and autoregulation.

Entities:  

Year:  1999        PMID： 11390824     DOI： 10.1152/physiologyonline.1999.14.2.74

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  11 in total

1.  Skeletal muscle arteriolar function following myocardial infarction: Analysis of branch-order effects.

Authors:  Michael A Tevald; John D Lowman; Roland N Pittman
Journal:  Microvasc Res       Date:  2011-01-27       Impact factor: 3.514

Review 2.  Control of muscle blood flow during exercise: local factors and integrative mechanisms.

Authors:  I Sarelius; U Pohl
Journal:  Acta Physiol (Oxf)       Date:  2010-03-26       Impact factor: 6.311

Review 3.  Contribution of flow-dependent vasomotor mechanisms to the autoregulation of cerebral blood flow.

Authors:  Akos Koller; Peter Toth
Journal:  J Vasc Res       Date:  2012-06-22       Impact factor: 1.934

Review 4.  Pressure-induced myogenic tone and role of 20-HETE in mediating autoregulation of cerebral blood flow.

Authors:  David R Harder; Jayashree Narayanan; Debebe Gebremedhin
Journal:  Am J Physiol Heart Circ Physiol       Date:  2011-01-21       Impact factor: 4.733

5.  The early effects of chronic hypoxia on the cardiovascular system in the rat: role of nitric oxide.

Authors:  Martin P Walsh; Janice M Marshall
Journal:  J Physiol       Date:  2006-05-11       Impact factor: 5.182

6.  Gap junction protein Cx37 interacts with endothelial nitric oxide synthase in endothelial cells.

Authors:  Anna Pfenniger; Jean-Paul Derouette; Vandana Verma; Xianming Lin; Bernard Foglia; Wanda Coombs; Isabelle Roth; Nathalie Satta; Sylvie Dunoyer-Geindre; Paul Sorgen; Steven Taffet; Brenda R Kwak; Mario Delmar
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-01-15       Impact factor: 8.311

7.  Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans.

Authors:  Takashi Nakai; Nicholas R Perl; Timothy C Barden; Andrew Carvalho; Angelika Fretzen; Peter Germano; G-Yoon J Im; Hong Jin; Charles Kim; Thomas W-H Lee; Kimberly Long; Joel Moore; Jason M Rohde; Renee Sarno; Chrissie Segal; Erik O Solberg; Jenny Tobin; Daniel P Zimmer; Mark G Currie
Journal:  ACS Med Chem Lett       Date:  2016-02-24       Impact factor: 4.345

8.  Endothelial function in aorta segments of apolipoprotein E-deficient mice before development of atherosclerotic lesions.

Authors:  Paul Fransen; Tim Van Assche; Pieter-Jan Guns; Cor E Van Hove; Gilles W De Keulenaer; Arnold G Herman; Hidde Bult
Journal:  Pflugers Arch       Date:  2007-09-27       Impact factor: 3.657

9.  Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5.

Authors:  Jharon Silva; Oksana Polesskaya; Walter Knight; Johnny Ting Zheng; Megan Granger; Tenée Lopez; Fernando Ontiveros; Changyong Feng; Chen Yan; Karl A Kasischke; Stephen Dewhurst
Journal:  J Neuroinflammation       Date:  2012-11-20       Impact factor: 8.322

10.  Mechanisms of vasodilation in the dorsal aorta of the elephant fish, Callorhinchus milii (Chimaeriformes: Holocephali).

Authors:  Brett L Jennings; Justin D Bell; Susumu Hyodo; Tes Toop; John A Donald
Journal:  J Comp Physiol B       Date:  2007-03-07       Impact factor: 2.230
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