Literature DB >> 11390819

The Dual Role of Nitric Oxide in Islet beta-Cells.

Giatgen A. Spinas1.   

Abstract

In pancreatic islets, nitric oxide (NO) produced on exposure to cytokines mediates beta-cell injury leading to diabetes mellitus. On the other hand, L-arginine-derived NO may participate in the signal transduction pathway of physiological insulin secretion. This review focuses on the dual role of NO as a mediator of physiological and pathophysiological processes in pancreatic islets.

Entities:  

Year:  1999        PMID： 11390819     DOI： 10.1152/physiologyonline.1999.14.2.49

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  26 in total

1.  Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2.

Authors:  Elango Bhakkiyalakshmi; Devibalan Shalini; Thillai Veerapazham Sekar; Palanisamy Rajaguru; Ramasamy Paulmurugan; Kunka Mohanram Ramkumar
Journal:  Br J Pharmacol       Date:  2014-04       Impact factor: 8.739

2.  Beneficial effect of S-allylcysteine (SAC) on blood glucose and pancreatic antioxidant system in streptozotocin diabetic rats.

Authors:  Ganapathy Saravanan; Ponnusamy Ponmurugan
Journal:  Plant Foods Hum Nutr       Date:  2010-12       Impact factor: 3.921

3.  S-allylcysteine Improves Streptozotocin-Induced Alterations of Blood Glucose, Liver Cytochrome P450 2E1, Plasma Antioxidant System, and Adipocytes Hormones in Diabetic Rats.

Authors:  Ganapathy Saravanan; Ponnusamy Ponmurugan
Journal:  Int J Endocrinol Metab       Date:  2013-10-01

4.  Modulation of glucose uptake in adipose tissue by nitric oxide-generating compounds.

Authors:  Donovan McGrowder; Dalip Ragoobirsingh; Paul Brown
Journal:  J Biosci       Date:  2006-09       Impact factor: 1.826

5.  Preventive effects of Cassia auriculata L. flowers on brain lipid peroxidation in rats treated with streptozotocin.

Authors:  Muniappan Latha; Leelavinothan Pari
Journal:  Mol Cell Biochem       Date:  2003-01       Impact factor: 3.396

6.  In vivo hypoglycemic, antihyperglycemic and antidyslipidemic effects of the solvent fractions of Hagenia abyssinica leaves in mice.

Authors:  Zemene Demelash Kifle; Alem Endeshaw Woldeyohanin; Faisel Dula Sema; Simachew Gidey Debeb; Asmamaw Emagn Kasahun; Chilot Abiyu Demeke; Yaschilal Muche Belayneh
Journal:  Metabol Open       Date:  2021-10-14

7.  Evaluation of Antidiabetic and Antioxidant Activity of Leaf Extract and Solvent Fractions of Hypoestes forskaolii (Val) (Acanthaceae) in Mice.

Authors:  Wakuma Wakene; Solomon Asmamaw; Wubayehu Kahaliw
Journal:  J Exp Pharmacol       Date:  2021-08-22

Review 8.  Regulation of obesity and insulin resistance by nitric oxide.

Authors:  Brian E Sansbury; Bradford G Hill
Journal:  Free Radic Biol Med       Date:  2014-05-28       Impact factor: 7.376

9.  Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated.

Authors:  Shiva Reddy; Lars Krogvold; Charlton Martin; Kevin Xueying Sun; Owen Martin; Aamenah Al-Ani; Knut Dahl-Jørgensen
Journal:  Cell Tissue Res       Date:  2021-01-11       Impact factor: 5.249

10.  Anti-diabetic potential of Sapium ellipticum (Hochst) Pax leaf extract in Streptozotocin(STZ)-induced diabetic Wistar rats.

Authors:  Osasenaga Macdonald Ighodaro; Oluseyi Adeboye Akinloye
Journal:  BMC Complement Altern Med       Date:  2017-12-08       Impact factor: 3.659
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