Literature DB >> 11390805

Understanding the Physiology of the Blood-Brain Barrier: In Vitro Models.

Gerald A. Grant1, N. Joan Abbott, Damir Janigro.   

Abstract

Endothelial cells exposed to inductive central nervous system factors differentiate into a blood-brain barrier phenotype. The blood-brain barrier frequently obstructs the passage of chemotherapeutics into the brain. Tissue culture systems have been developed to reproduce key properties of the intact blood-brain barrier and to allow for testing of mechanisms of transendothelial drug permeation.

Year:  1998        PMID： 11390805     DOI： 10.1152/physiologyonline.1998.13.6.287

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  21 in total

1.  Monocytes form a vascular barrier and participate in vessel repair after brain injury.

Authors:  John Glod; David Kobiler; Martha Noel; Rajeth Koneru; Shoshana Lehrer; Daniel Medina; Dragan Maric; Howard A Fine
Journal:  Blood       Date:  2005-10-04       Impact factor: 22.113

2.  Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells.

Authors:  Hdikó Sipos; Beáta Törocsik; Laszlo Tretter; Vera Adam-Vizi
Journal:  Cell Mol Neurobiol       Date:  2005-02       Impact factor: 5.046

Review 3.  3D in vitro modeling of the central nervous system.

Authors:  Amy M Hopkins; Elise DeSimone; Karolina Chwalek; David L Kaplan
Journal:  Prog Neurobiol       Date:  2014-11-22       Impact factor: 11.685

Review 4.  On the genealogy of tissue engineering and regenerative medicine.

Authors:  Himanshu Kaul; Yiannis Ventikos
Journal:  Tissue Eng Part B Rev       Date:  2014-12-23       Impact factor: 6.389

5.  A pro-convulsive carbamazepine metabolite: quinolinic acid in drug resistant epileptic human brain.

Authors:  Chaitali Ghosh; Nicola Marchi; Mohammed Hossain; Peter Rasmussen; Andreas V Alexopoulos; Jorge Gonzalez-Martinez; Hu Yang; Damir Janigro
Journal:  Neurobiol Dis       Date:  2012-03-09       Impact factor: 5.996

Review 6.  In vitro blood-brain barrier models: current and perspective technologies.

Authors:  Pooja Naik; Luca Cucullo
Journal:  J Pharm Sci       Date:  2011-12-27       Impact factor: 3.534

Review 7.  Neuronal and vascular interactions.

Authors:  Benjamin J Andreone; Baptiste Lacoste; Chenghua Gu
Journal:  Annu Rev Neurosci       Date:  2015-03-12       Impact factor: 12.449

8.  Occludin as direct target for glucocorticoid-induced improvement of blood-brain barrier properties in a murine in vitro system.

Authors:  Carola Förster; Christine Silwedel; Nikola Golenhofen; Malgorzata Burek; Silke Kietz; Joachim Mankertz; Detlev Drenckhahn
Journal:  J Physiol       Date:  2005-03-24       Impact factor: 5.182

9.  Persistent SIV infection of a blood-brain barrier model.

Authors:  Lisa Strelow; Damir Janigro; Jay A Nelson
Journal:  J Neurovirol       Date:  2002-08       Impact factor: 2.643

Review 10.  Cell-culture models of the blood-brain barrier.

Authors:  Yarong He; Yao Yao; Stella E Tsirka; Yu Cao
Journal:  Stroke       Date:  2014-06-17       Impact factor: 7.914
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