Literature DB >> 11390785

Fast Inactivation of Voltage-Gated K(+) Channels: From Cartoon to Structure.

Christoph Antz1, Bernd Fakler.   

Abstract

Fast inactivation of voltage-gated potassium (K(v)) channels is the best understood gating transition in ion channels and is brought about by an NH(2)-terminal domain (ball domain) of the channel's alpha-subunit, which physically blocks the open pore. Recent analysis by nuclear magnetic resonance spectroscopy showed that ball domains from various K(v) channels exhibit well-defined but distinct structures in aqueous solution.

Year:  1998        PMID： 11390785     DOI： 10.1152/physiologyonline.1998.13.4.177

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  8 in total

1.  Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2.

Authors:  Niels Decher; Teresa Gonzalez; Anne Kathrin Streit; Frank B Sachse; Vijay Renigunta; Malle Soom; Stefan H Heinemann; Jürgen Daut; Michael C Sanguinetti
Journal:  EMBO J       Date:  2008-11-06       Impact factor: 11.598

2.  Electrostatic interactions during Kv1.2 N-type inactivation: random-walk simulation.

Authors:  Krzysztof Małysiak; Zbigniew J Grzywna
Journal:  Eur Biophys J       Date:  2009-06-18       Impact factor: 1.733

3.  Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain.

Authors:  Gamma Chi; Qiansheng Liang; Akshay Sridhar; John B Cowgill; Kasim Sader; Mazdak Radjainia; Pu Qian; Pablo Castro-Hartmann; Shayla Venkaya; Nanki Kaur Singh; Gavin McKinley; Alejandra Fernandez-Cid; Shubhashish M M Mukhopadhyay; Nicola A Burgess-Brown; Lucie Delemotte; Manuel Covarrubias; Katharina L Dürr
Journal:  Nat Commun       Date:  2022-07-15       Impact factor: 17.694

Review 4.  Oxidative modulation of voltage-gated potassium channels.

Authors:  Nirakar Sahoo; Toshinori Hoshi; Stefan H Heinemann
Journal:  Antioxid Redox Signal       Date:  2013-10-26       Impact factor: 8.401

Review 5.  Physiological modulation of inactivation in L-type Ca2+ channels: one switch.

Authors:  Ian Findlay
Journal:  J Physiol       Date:  2003-06-24       Impact factor: 5.182

6.  Heme impairs the ball-and-chain inactivation of potassium channels.

Authors:  Nirakar Sahoo; Nishit Goradia; Oliver Ohlenschläger; Roland Schönherr; Manfred Friedrich; Winfried Plass; Reinhard Kappl; Toshinori Hoshi; Stefan H Heinemann
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-30       Impact factor: 11.205

7.  Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

Authors:  Gamma Chi; Rebecca Ebenhoch; Henry Man; Haiping Tang; Laurence E Tremblay; Gabriella Reggiano; Xingyu Qiu; Tina Bohstedt; Idlir Liko; Fernando G Almeida; Alexandre P Garneau; Dong Wang; Gavin McKinley; Christophe P Moreau; Kiran D Bountra; Patrizia Abrusci; Shubhashish M M Mukhopadhyay; Alejandra Fernandez-Cid; Samira Slimani; Julie L Lavoie; Nicola A Burgess-Brown; Ben Tehan; Frank DiMaio; Ali Jazayeri; Paul Isenring; Carol V Robinson; Katharina L Dürr
Journal:  EMBO J       Date:  2021-05-25       Impact factor: 14.012

8.  On the possible methods for the mathematical description of the ball and chain model of ion channel inactivation.

Authors:  Krzysztof Małysiak; Zbigniew J Grzywna
Journal:  Cell Mol Biol Lett       Date:  2008-05-10       Impact factor: 5.787
  8 in total

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