Literature DB >> 11390784

Unraveling the Mystery of Goldblatt Hypertension.

L. Gabriel Navar1, Lixian Zou, Annette Von Thun, Chi Tarng Wang, John D. Imig, Kenneth D. Mitchell.   

Abstract

In hypertension caused by unilateral renal artery stenosis, the nonstenotic kidney becomes renin depleted but fails to prevent hypertension. The nonstenotic kidney mysteriously develops elevated intrarenal angiotensin II (ANG II) content. Rats chronically infused with ANG II exhibit a similar hypertensive process. The augmentation of intrarenal ANG II is due to receptor-mediated internalization and continued ANG II formation, which provide a hypertensinogenic stimulus.

Entities:  

Year:  1998        PMID： 11390784     DOI： 10.1152/physiologyonline.1998.13.4.170

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  39 in total

1.  Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension.

Authors:  Luis C Matavelli; Jiqian Huang; Helmy M Siragy
Journal:  Hypertension       Date:  2010-12-28       Impact factor: 10.190

Review 2.  Proximal nephron.

Authors:  Jia L Zhuo; Xiao C Li
Journal:  Compr Physiol       Date:  2013-07       Impact factor: 9.090

3.  AT1 receptors in the subfornical organ modulate arterial pressure and the baroreflex in two-kidney, one-clip hypertensive rats.

Authors:  Noreen F Rossi; Zachary Zenner; Arun K Rishi; Edi Levi; Maria Maliszewska-Scislo
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2019-01-09       Impact factor: 3.619

Review 4.  The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases.

Authors:  Xiao C Li; Jianfeng Zhang; Jia L Zhuo
Journal:  Pharmacol Res       Date:  2017-06-12       Impact factor: 7.658

5.  Increased expression of angiotensin II type 2 receptors in the solitary-vagal complex blunts renovascular hypertension.

Authors:  Graziela Torres Blanch; André Henrique Freiria-Oliveira; Guilherme Fleury Fina Speretta; Eduardo J Carrera; Hongwei Li; Robert C Speth; Eduardo Colombari; Colin Sumners; Débora S A Colombari
Journal:  Hypertension       Date:  2014-06-23       Impact factor: 10.190

6.  Effects of salt loading on sympathetic activity and blood pressure in anesthetized two-kidney, one clip hypertensive rats.

Authors:  Besim Ozaykan; Ayşe Doğan
Journal:  Bosn J Basic Med Sci       Date:  2011-11       Impact factor: 3.363

7.  Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats.

Authors:  Alexandra Sporková; Libor Kopkan; Sárka Varcabová; Zuzana Husková; Sung Hee Hwang; Bruce D Hammock; John D Imig; Herbert J Kramer; Ludek Cervenka
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-03-16       Impact factor: 3.619

8.  Augmentation of angiotensinogen expression in the proximal tubule by intracellular angiotensin II via AT1a/MAPK/NF-кB signaling pathways.

Authors:  Jia L Zhuo; H Kobori; Xiao C Li; R Satou; A Katsurada; L Gabriel Navar
Journal:  Am J Physiol Renal Physiol       Date:  2016-02-10

9.  Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.

Authors:  Agnieszka Walkowska; Petra Skaroupková; Zuzana Husková; Zdenka Vanourková; Vera Certíková Chábová; Vladimír Tesar; Herbert J Kramer; John R Falck; John D Imig; Elzbieta Kompanowska-Jezierska; Janusz Sadowski; Ludek Cervenka
Journal:  J Hypertens       Date:  2010-03       Impact factor: 4.844

10.  Effects of allisartan, a new AT(1) receptor blocker, on blood pressure and end-organ damage in hypertensive animals.

Authors:  Ming-yue Wu; Xiu-juan Ma; Chu Yang; Xia Tao; Ai-jun Liu; Ding-feng Su; Jian-guo Liu
Journal:  Acta Pharmacol Sin       Date:  2009-03       Impact factor: 6.150
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