Literature DB >> 11390753

Killing Mechanisms of Cytotoxic T Lymphocytes.

Peter Groscurth1, Luis Filgueira.   

Abstract

Cytotoxic T lymphocytes mediate lysis of target cells by various mechanisms, including exocytosis of lytic proteins (perforin, granzymes) and receptor-ligand binding of Fas/APO molecules. Death of target cells is characterized by either necrosis or apoptosis, depending on the killing mechanism used and on the metabolism of the target cell itself.

Entities:  

Year:  1998        PMID： 11390753     DOI： 10.1152/physiologyonline.1998.13.1.17

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  10 in total

Review 1.  Aiming to immune elimination of ovarian cancer stem cells.

Authors:  Jiabo Di; Tjitske Duiveman-de Boer; Carl G Figdor; Ruurd Torensma
Journal:  World J Stem Cells       Date:  2013-10-26       Impact factor: 5.326

Review 2.  Pathogenesis and mechanisms of antibody-mediated hemolysis.

Authors:  Willy A Flegel
Journal:  Transfusion       Date:  2015-07       Impact factor: 3.157

Review 3.  In-situ tumor vaccination: Bringing the fight to the tumor.

Authors:  Robert H Pierce; Jean S Campbell; Sara I Pai; Joshua D Brody; Holbrook E K Kohrt
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

Review 4.  DNA vaccines, electroporation and their applications in cancer treatment.

Authors:  Si-Hyeong Lee; Sayyed Nilofar Danishmalik; Jeong-Im Sin
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

5.  Stochastic model of T cell repolarization during target elimination (II).

Authors:  Ivan Hornak; Heiko Rieger
Journal:  Biophys J       Date:  2022-02-20       Impact factor: 3.699

6.  Adoptive transfer of human papillomavirus E7-specific CTL enhances tumor chemoresponse through the perforin/granzyme-mediated pathway.

Authors:  Jeong-Im Sin; Jung-Min Kim; Sung Hwa Bae; In Hee Lee; Jong Sup Park; Hun Mo Ryoo
Journal:  Mol Ther       Date:  2009-03-10       Impact factor: 11.454

7.  A modern approach for epitope prediction: identification of foot-and-mouth disease virus peptides binding bovine leukocyte antigen (BoLA) class I molecules.

Authors:  Mital Pandya; Michael Rasmussen; Andreas Hansen; Morten Nielsen; Soren Buus; William Golde; John Barlow
Journal:  Immunogenetics       Date:  2015-11       Impact factor: 2.846

8.  Allogeneic ADSCs induce CD8 T cell-mediated cytotoxicity and faster cell death after exposure to xenogeneic serum or proinflammatory cytokines.

Authors:  Sung-Ho Chang; Chung-Gyu Park
Journal:  Exp Mol Med       Date:  2019-03-11       Impact factor: 8.718

Review 9.  Understanding the Immune-Stroma Microenvironment in B Cell Malignancies for Effective Immunotherapy.

Authors:  Benedetta Apollonio; Nikolaos Ioannou; Despoina Papazoglou; Alan G Ramsay
Journal:  Front Oncol       Date:  2021-03-25       Impact factor: 6.244

Review 10.  Recent Advances: The Imbalance of Immune Cells and Cytokines in the Pathogenesis of Hepatocellular Carcinoma.

Authors:  Kumar Jayant; Nagy Habib; Kai W Huang; Jane Warwick; Ramesh Arasaradnam
Journal:  Diagnostics (Basel)       Date:  2020-05-25
  10 in total

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