Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer.

Literature DB >> 11390622

Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer.

M Hildinger¹, A Auricchio, G Gao, L Wang, N Chirmule, J M Wilson.

Abstract

Vectors based on hybrids consisting of adeno-associated virus types 2 (ITRs and Rep) and 5 (Cap) were evaluated for muscle-directed gene transfer (called AAV2/5). Evaluation in immune-competent mice revealed greater transduction efficacy with AAV2/5 than with AAV2 and no cross-neutralization between AAV2/5 and AAV2. Interestingly, we saw no immunologic evidence of previous exposure to AAV5 capsids in a large population of healthy human subjects.

Entities: Chemical

Mesh：

Substances：
Antibodies, Viral

Year: 2001 PMID： 11390622 PMCID： PMC114336 DOI： 10.1128/JVI.75.13.6199-6203.2001

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

18 in total

1. Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors.

Authors: H Chao; Y Liu; J Rabinowitz; C Li; R J Samulski; C E Walsh
Journal: Mol Ther Date: 2000-12 Impact factor: 11.454

2. Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles.

Authors: J A Chiorini; L Yang; Y Liu; B Safer; R M Kotin
Journal: J Virol Date: 1997-09 Impact factor: 5.103

3. Immune responses to adenovirus and adeno-associated virus in humans.

Authors: N Chirmule; K Propert; S Magosin; Y Qian; R Qian; J Wilson
Journal: Gene Ther Date: 1999-09 Impact factor: 5.250

4. Recombinant adeno-associated virus for muscle directed gene therapy.

Authors: K J Fisher; K Jooss; J Alston; Y Yang; S E Haecker; K High; R Pathak; S E Raper; J M Wilson
Journal: Nat Med Date: 1997-03 Impact factor: 53.440

5. Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer.

Authors: J Zabner; M Seiler; R Walters; R M Kotin; W Fulgeras; B L Davidson; J A Chiorini
Journal: J Virol Date: 2000-04 Impact factor: 5.103

6. Additional transduction events after subretinal readministration of recombinant adeno-associated virus.

Authors: V Anand; N Chirmule; M Fersh; A M Maguire; J Bennett
Journal: Hum Gene Ther Date: 2000-02-10 Impact factor: 5.695

7. Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2.

Authors: E A Rutledge; C L Halbert; D W Russell
Journal: J Virol Date: 1998-01 Impact factor: 5.103

8. Analysis of proteins, helper dependence, and seroepidemiology of a new human parvovirus.

Authors: B Georg-Fries; S Biederlack; J Wolf; H zur Hausen
Journal: Virology Date: 1984-04-15 Impact factor: 3.616

9. Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column.

Authors: A Auricchio; M Hildinger; E O'Connor; G P Gao; J M Wilson
Journal: Hum Gene Ther Date: 2001-01-01 Impact factor: 5.695

10. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

Authors: B L Davidson; C S Stein; J A Heth; I Martins; R M Kotin; T A Derksen; J Zabner; A Ghodsi; J A Chiorini
Journal: Proc Natl Acad Sci U S A Date: 2000-03-28 Impact factor: 11.205

71 in total

Review 1. Adenoassociated virus vectors for genetic immunization.

Authors: Selvarangan Ponnazhagan
Journal: Immunol Res Date: 2002 Impact factor: 2.829

2. Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain.

Authors: Mihail Y Mastakov; Kristin Baer; C Wymond Symes; Claudia B Leichtlein; Robert M Kotin; Matthew J During
Journal: J Virol Date: 2002-08 Impact factor: 5.103

3. The long noncoding RNA Vax2os1 controls the cell cycle progression of photoreceptor progenitors in the mouse retina.

Authors: Nicola Meola; Mariateresa Pizzo; Giovanna Alfano; Enrico Maria Surace; Sandro Banfi
Journal: RNA Date: 2011-11-29 Impact factor: 4.942

4. Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.

Authors: Chengwen Li; Nina Diprimio; Dawn E Bowles; Matthew L Hirsch; Paul E Monahan; Aravind Asokan; Joseph Rabinowitz; Mavis Agbandje-McKenna; R Jude Samulski
Journal: J Virol Date: 2012-05-16 Impact factor: 5.103

5. Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6.

Authors: Zhijian Wu; Edward Miller; Mavis Agbandje-McKenna; Richard Jude Samulski
Journal: J Virol Date: 2006-09 Impact factor: 5.103

6. Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system.

Authors: Erik Kohlbrenner; George Aslanidi; Kevin Nash; Stanislav Shklyaev; Martha Campbell-Thompson; Barry J Byrne; Richard O Snyder; Nicholas Muzyczka; Kenneth H Warrington; Sergei Zolotukhin
Journal: Mol Ther Date: 2005-10-06 Impact factor: 11.454

7. Viral serotype and the transgene sequence influence overlapping adeno-associated viral (AAV) vector-mediated gene transfer in skeletal muscle.

Authors: Arkasubhra Ghosh; Yongping Yue; Dongsheng Duan
Journal: J Gene Med Date: 2006-03 Impact factor: 4.565