Literature DB >> 11390369

A multiprotein complex that interacts with RNA polymerase II elongator.

Y Li1, Y Takagi, Y Jiang, M Tokunaga, H Erdjument-Bromage, P Tempst, R D Kornberg.   

Abstract

A three-subunit Hap complex that interacts with the RNA polymerase II Elongator was isolated from yeast. Deletions of genes for two Hap subunits, HAP1 and HAP3, confer pGKL killer-insensitive and weak Elongator phenotypes. Preferential interaction of the Hap complex with free rather than RNA polymerase II-associated Elongator suggests a role in the regulation of Elongator activity.

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Year:  2001        PMID： 11390369     DOI： 10.1074/jbc.C100274200

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  26 in total

1.  Crystal structure of elongator subcomplex Elp4-6.

Authors:  Zhijie Lin; Weijing Zhao; Wentao Diao; Xingqiao Xie; Zheng Wang; Jinxiu Zhang; Yuequan Shen; Jiafu Long
Journal:  J Biol Chem       Date:  2012-05-02       Impact factor: 5.157

2.  Human Elongator facilitates RNA polymerase II transcription through chromatin.

Authors:  Jae-Hyun Kim; William S Lane; Danny Reinberg
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-29       Impact factor: 11.205

Review 3.  The role of the Elongator complex in plants.

Authors:  Christopher DeFraia; Zhonglin Mou
Journal:  Plant Signal Behav       Date:  2011-01-01

4.  Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo.

Authors:  G Sebastiaan Winkler; Arnold Kristjuhan; Hediye Erdjument-Bromage; Paul Tempst; Jesper Q Svejstrup
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-19       Impact factor: 11.205

5.  Loss of ncm5 and mcm5 wobble uridine side chains results in an altered metabolic profile.

Authors:  Hasan Tükenmez; Tony Karlsborn; A K M Firoj Mahmud; Anders S Byström
Journal:  Metabolomics       Date:  2016-09-27       Impact factor: 4.290

6.  The Elp3 subunit of human Elongator complex is functionally similar to its counterpart in yeast.

Authors:  Fen Li; Jun Lu; Qiuju Han; Guoping Zhang; Baiqu Huang
Journal:  Mol Genet Genomics       Date:  2005-04-16       Impact factor: 3.291

7.  Tissue-specific reduction in splicing efficiency of IKBKAP due to the major mutation associated with familial dysautonomia.

Authors:  Math P Cuajungco; Maire Leyne; James Mull; Sandra P Gill; Weining Lu; David Zagzag; Felicia B Axelrod; Channa Maayan; James F Gusella; Susan A Slaugenhaupt
Journal:  Am J Hum Genet       Date:  2003-02-06       Impact factor: 11.025

8.  The tRNA modification complex elongator regulates the Cdc42-dependent mitogen-activated protein kinase pathway that controls filamentous growth in yeast.

Authors:  Ummi Abdullah; Paul J Cullen
Journal:  Eukaryot Cell       Date:  2009-07-24

9.  Mutant casein kinase I (Hrr25p/Kti14p) abrogates the G1 cell cycle arrest induced by Kluyveromyces lactiszymocin in budding yeast.

Authors:  C Mehlgarten; R Schaffrath
Journal:  Mol Genet Genomics       Date:  2003-02-13       Impact factor: 3.291

Review 10.  Structural insights into the function of Elongator.

Authors:  Udit Dalwadi; Calvin K Yip
Journal:  Cell Mol Life Sci       Date:  2018-01-13       Impact factor: 9.261
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