Literature DB >> 11390008

Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung.

A M Malkinson1.   

Abstract

Primary lung tumors in mice have morphologic, histogenic, and molecular features similar to human lung adenocarcinoma, and in particular, the bronchiolo-alveolar carcinoma subtype. Because of this, and because of the genetic homology between man and mouse and the ease of genetic manipulations in mice, this model system is receiving intense research attention. This review is intended to be informative to clinical investigators, and describes features of this model, how it is being used for translational research, and points out additional avenues of study that could have practical benefits, such as application for identifying novel therapeutic strategies.

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Year:  2001        PMID： 11390008     DOI： 10.1016/s0169-5002(00)00232-4

Source DB:  PubMed          Journal:  Lung Cancer        ISSN： 0169-5002            Impact factor:   5.705


  44 in total

1.  Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression.

Authors:  Robert L Keith; Vijaya Karoor; Anthony B Mozer; Tyler M Hudish; Mysan Le; York E Miller
Journal:  Lung Cancer       Date:  2010-01-29       Impact factor: 5.705

Review 2.  Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.

Authors:  Mathew Suji Eapen; Philip M Hansbro; Anna-Karin Larsson-Callerfelt; Mohit K Jolly; Stephen Myers; Pawan Sharma; Bernadette Jones; Md Atiqur Rahman; James Markos; Collin Chia; Josie Larby; Greg Haug; Ashutosh Hardikar; Heinrich C Weber; George Mabeza; Vinicius Cavalheri; Yet H Khor; Christine F McDonald; Sukhwinder Singh Sohal
Journal:  Drugs       Date:  2018-11       Impact factor: 9.546

3.  Chemopreventive effects of the p53-modulating agents CP-31398 and Prima-1 in tobacco carcinogen-induced lung tumorigenesis in A/J mice.

Authors:  Chinthalapally V Rao; Jagan Mohan R Patlolla; Li Qian; Yuting Zhang; Misty Brewer; Altaf Mohammed; Dhimant Desai; Shantu Amin; Stan Lightfoot; Levy Kopelovich
Journal:  Neoplasia       Date:  2013-09       Impact factor: 5.715

Review 4.  Pathogenesis of lung cancer: 100 year report.

Authors:  York E Miller
Journal:  Am J Respir Cell Mol Biol       Date:  2005-09       Impact factor: 6.914

5.  Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice.

Authors:  Elizabeth F Redente; David J Orlicky; Ronald J Bouchard; Alvin M Malkinson
Journal:  Am J Pathol       Date:  2007-02       Impact factor: 4.307

6.  Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice.

Authors:  Qi Hu; Pedro Corral; Sreekanth C Narayanapillai; Pablo Leitzman; Pramod Upadhyaya; M Gerard O'Sullivan; Stephen S Hecht; Junxuan Lu; Chengguo Xing
Journal:  Chem Res Toxicol       Date:  2020-06-11       Impact factor: 3.739

Review 7.  Harnessing preclinical mouse models to inform human clinical cancer trials.

Authors:  David H Gutmann; Kim Hunter-Schaedle; Kevin M Shannon
Journal:  J Clin Invest       Date:  2006-04       Impact factor: 14.808

8.  Epistatic interactions govern chemically-induced lung tumor susceptibility and Kras mutation site in murine C57BL/6J-ChrA/J chromosome substitution strains.

Authors:  Lori D Dwyer-Nield; Jay McQuillan; Annie Hill-Baskin; Richard A Radcliffe; Ming You; Joseph H Nadeau; Alvin M Malkinson
Journal:  Int J Cancer       Date:  2010-01-01       Impact factor: 7.396

9.  Allergic inflammation does not impact chemical-induced carcinogenesis in the lungs of mice.

Authors:  Konstantinos Doris; Sophia P Karabela; Chrysoula A Kairi; Davina Cm Simoes; Charis Roussos; Spyros G Zakynthinos; Ioannis Kalomenidis; Timothy S Blackwell; Georgios T Stathopoulos
Journal:  Respir Res       Date:  2010-08-26

10.  Repeated aerosol delivery of carboxyl-terminal modulator protein suppresses tumor in the lungs of K-rasLA1 mice.

Authors:  Soon-Kyung Hwang; Hwang-Tae Lim; Arash Minai-Tehrani; Eun-Sun Lee; Jongmin Park; Seung Bum Park; George R Beck; Myung-Haing Cho
Journal:  Am J Respir Crit Care Med       Date:  2009-03-12       Impact factor: 21.405
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