Literature DB >> 11389480

Microarrays in brain research: the good, the bad and the ugly.

K Mirnics1.   

Abstract

Making sense of microarray data is a complex process, in which the interpretation of findings will depend on the overall experimental design and judgement of the investigator performing the analysis. As a result, differences in tissue harvesting, microarray types, sample labelling and data analysis procedures make post hoc sharing of microarray data a great challenge. To ensure rapid and meaningful data exchange, we need to create some order out of the existing chaos. In these ground-breaking microarray standardization and data sharing efforts, NIH agencies should take a leading role

Mesh:

Year:  2001        PMID: 11389480     DOI: 10.1038/35077587

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN: 1471-003X            Impact factor:   34.870


  12 in total

1.  Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach.

Authors:  Qing Zhao; Alvin Kho; Anna Marie Kenney; Dong-in Yuk Di; Isaac Kohane; David H Rowitch
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

Review 2.  Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders.

Authors:  Julie Pongrac; Frank A Middleton; David A Lewis; Pat Levitt; Károly Mirnics
Journal:  Neurochem Res       Date:  2002-10       Impact factor: 3.996

Review 3.  Methodological considerations regarding single-cell gene expression profiling for brain injury.

Authors:  Jason E Davis; James H Eberwine; David A Hinkle; Paolo G Marciano; David F Meaney; Tracy K McIntosh
Journal:  Neurochem Res       Date:  2004-06       Impact factor: 3.996

4.  Microarray and real-time PCR analyses of gene expression in the honeybee brain following caffeine treatment.

Authors:  Robert Kucharski; Ryszard Maleszka
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

Review 5.  Central nervous system drug development: an integrative biomarker approach toward individualized medicine.

Authors:  B Gomez-Mancilla; E Marrer; J Kehren; A Kinnunen; G Imbert; R Hillebrand; M Bergström; M E Schmidt
Journal:  NeuroRx       Date:  2005-10

Review 6.  Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening.

Authors:  Giorgio Gorini; Richard L Bell; R Dayne Mayfield
Journal:  Prog Mol Biol Transl Sci       Date:  2011       Impact factor: 3.622

Review 7.  Analyzing schizophrenia by DNA microarrays.

Authors:  Szatmár Horváth; Zoltán Janka; Károly Mirnics
Journal:  Biol Psychiatry       Date:  2011-01-15       Impact factor: 13.382

8.  A study of gene expression profiles of cultured embryonic rat neurons induced by phenylalanine.

Authors:  Huiwen Zhang; Xue Fan Gu
Journal:  Metab Brain Dis       Date:  2005-03       Impact factor: 3.584

9.  A flanking gene problem leads to the discovery of a Gprc5b splice variant predominantly expressed in C57Bl/6J mouse brain and in maturing neurons.

Authors:  Bethany H Cool; Guy C-K Chan; Lin Lee; Junko Oshima; George M Martin; Qubai Hu
Journal:  PLoS One       Date:  2010-04-26       Impact factor: 3.240

Review 10.  A molecular description of brain trauma pathophysiology using microarray technology: an overview.

Authors:  Pramod K Dash; Nobuhide Kobori; Anthony N Moore
Journal:  Neurochem Res       Date:  2004-06       Impact factor: 3.996

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