Literature DB >> 11387631

Interpretation of complex forensic DNA mixtures.

C Ladd1, H C Lee, N Yang, F R Bieber.   

Abstract

Forensic evidentiary samples routinely contain DNA from multiple contributors. The interpretation of these mixtures can be a challenging task for the DNA scientist. Several approaches are discussed (no calculation- qualitative statement; probability of exclusion; likelihood ratio estimates; presumptive genotype assignment based on peak heights), which have been employed to assess the significance of an inclusion/match when DNA mixtures have been detected in casework samples. These statistical approaches are discussed in light of technical challenges that can arise when evaluating evidentiary samples.

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Year:  2001        PMID： 11387631

Source DB:  PubMed          Journal:  Croat Med J        ISSN： 0353-9504            Impact factor:   1.351


  9 in total

1.  Evaluating Mixture Solution™- rapid and non-MCMC probabilistic mixture analysis.

Authors:  Anton Lucassen; Karen Ehlers; Paul J Grobler; Charles H Brenner
Journal:  Int J Legal Med       Date:  2021-10-01       Impact factor: 2.686

2.  An information gap in DNA evidence interpretation.

Authors:  Mark W Perlin; Alexander Sinelnikov
Journal:  PLoS One       Date:  2009-12-16       Impact factor: 3.240

Review 3.  Laser capture microdissection in forensic research: a review.

Authors:  Mado Vandewoestyne; Dieter Deforce
Journal:  Int J Legal Med       Date:  2010-08-03       Impact factor: 2.686

4.  The genotypic structure of a multi-host bumblebee parasite suggests a role for ecological niche overlap.

Authors:  Rahel M Salathé; Paul Schmid-Hempel
Journal:  PLoS One       Date:  2011-08-10       Impact factor: 3.240

5.  Evaluation of forensic DNA mixture evidence: protocol for evaluation, interpretation, and statistical calculations using the combined probability of inclusion.

Authors:  Frederick R Bieber; John S Buckleton; Bruce Budowle; John M Butler; Michael D Coble
Journal:  BMC Genet       Date:  2016-08-31       Impact factor: 2.797

6.  A novel multiplex assay of SNP-STR markers for forensic purpose.

Authors:  Tian Wei; Fei Liao; Yaowu Wang; Chao Pan; Chao Xiao; Daixin Huang
Journal:  PLoS One       Date:  2018-07-18       Impact factor: 3.240

7.  Revisiting single cell analysis in forensic science.

Authors:  Davis R L Watkins; Dan Myers; Hannah E Xavier; Michael A Marciano
Journal:  Sci Rep       Date:  2021-03-29       Impact factor: 4.379

8.  Internal Validation of MaSTR™ Probabilistic Genotyping Software for the Interpretation of 2-5 Person Mixed DNA Profiles.

Authors:  Michael S Adamowicz; Taylor N Rambo; Jennifer L Clarke
Journal:  Genes (Basel)       Date:  2022-08-11       Impact factor: 4.141

9.  Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

Authors:  Nils Homer; Szabolcs Szelinger; Margot Redman; David Duggan; Waibhav Tembe; Jill Muehling; John V Pearson; Dietrich A Stephan; Stanley F Nelson; David W Craig
Journal:  PLoS Genet       Date:  2008-08-29       Impact factor: 5.917
  9 in total

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