Literature DB >> 113876

Organization of the immune response genes.

J W Uhr, J D Capra, E S Vitetta, R G Cook.   

Abstract

The I region of the major histocompatibility complex contains immune response genes that display considerable polymorphism; that is, there are many alleles at each locus. These genes regulate the immune response to antigen by mediating intercellular communication among lymphoreticular cells. An analysis of the primary structure of the products of two subregions of (I-A, I-E/C) was undertaken in order to understand the genetic organization of the region, the evolution of the genes and, eventually, their function.

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Year:  1979        PMID: 113876     DOI: 10.1126/science.113876

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  50 in total

Review 1.  Ancestral polymorphisms of MHC class II genes: divergent allele advantage.

Authors:  E K Wakeland; S Boehme; J X She; C C Lu; R A McIndoe; I Cheng; Y Ye; W K Potts
Journal:  Immunol Res       Date:  1990       Impact factor: 2.829

2.  Cotransfer of the Ed alpha and Ad beta genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule.

Authors:  B Malissen; N Shastri; M Pierres; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

3.  Class I and class II restriction pattern polymorphisms associated with independently derived RT1 haplotypes in inbred rats.

Authors:  P J Wettstein; S Faas; D A Buck
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

4.  Ia-transfected L-cell fibroblasts present a lysozyme peptide but not the native protein to lysozyme-specific T cells.

Authors:  N Shastri; B Malissen; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

5.  A decrease in the estimated frequency of the extended HLA haplotype B18 CF130 DR3 DQw2 is common to non-insulin-dependent diabetes, juvenile rheumatoid arthritis, and Berger's disease.

Authors:  J R Regueiro; A Arnaiz-Villena; J L Vicario; J Martinez-Laso; A Pacheco; J M Rivera-Guzman
Journal:  Experientia       Date:  1993-07-05

6.  A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes.

Authors:  F M Brodsky
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

7.  Clonal analysis of the specificity of alloreactive cells: "dominance" of E beta reactive clones.

Authors:  G Pobor; S Pettersson; A Coutinho
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

8.  Genetic control of T-cell proliferative responses to poly(glu40ala60) and poly(glu51lys34tyr15): subregion-specific inhibition of the responses with monoclonal Ia antibodies.

Authors:  C N Baxevanis; D Wernet; Z A Nagy; P H Maurer; J Klein
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

9.  Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen.

Authors:  D A Shackelford; D L Mann; J J van Rood; G B Ferrara; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205

10.  Cell surface properties of HLA antigens on Epstein-Barr virus-transformed cell lines.

Authors:  L M Smith; H R Petty; P Parham; H M McConnell
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

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