Literature DB >> 11385723

Behavioral phenotyping of transgenic and knockout animals: a cautionary tale.

S D Bilbo1, R J Nelson.   

Abstract

Knockout and transgenic mice are extremely useful for behavioral research, especially for linking specific genes with behaviors. The authors present caveats to be aware of when using such mice in research situations.

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Mesh:

Year:  2001        PMID: 11385723

Source DB:  PubMed          Journal:  Lab Anim (NY)        ISSN: 0093-7355            Impact factor:   12.625


  4 in total

1.  Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains.

Authors:  Sheryl S Moy; Jessica J Nadler; Nancy B Young; Antonio Perez; L Paige Holloway; Ryan P Barbaro; Justin R Barbaro; Lindsay M Wilson; David W Threadgill; Jean M Lauder; Terry R Magnuson; Jacqueline N Crawley
Journal:  Behav Brain Res       Date:  2006-09-12       Impact factor: 3.332

Review 2.  Small G protein signaling in neuronal plasticity and memory formation: the specific role of ras family proteins.

Authors:  Xiaojing Ye; Thomas J Carew
Journal:  Neuron       Date:  2010-11-04       Impact factor: 17.173

Review 3.  Behavioural phenotyping assays for mouse models of autism.

Authors:  Jill L Silverman; Mu Yang; Catherine Lord; Jacqueline N Crawley
Journal:  Nat Rev Neurosci       Date:  2010-07       Impact factor: 34.870

Review 4.  Gene targeting of presynaptic proteins in synaptic plasticity and memory: across the great divide.

Authors:  Craig M Powell
Journal:  Neurobiol Learn Mem       Date:  2005-10-14       Impact factor: 2.877

  4 in total

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