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Literature DB >> 11385680

Preorganization of the Bioactive Conformation of Sialyl Lewis(X) Analogues Correlates with Their Affinity to E-Selectin.

Gebhard Thoma¹, John L. Magnani, John T. Patton, Beat Ernst, Wolfgang Jahnke.

Abstract

Entities: Gene

Year: 2001 PMID： 11385680

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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8 in total

1. GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice.

Authors: Jungshan Chang; John T Patton; Arun Sarkar; Beat Ernst; John L Magnani; Paul S Frenette
Journal: Blood Date: 2010-05-27 Impact factor: 22.113

2. Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow.

Authors: Vasilios A Morikis; Shannon Chase; Ted Wun; Elliot L Chaikof; John L Magnani; Scott I Simon
Journal: Blood Date: 2017-08-15 Impact factor: 22.113

3. Acyclic tethers mimicking subunits of polysaccharide ligands: selectin antagonists.

Authors: Mickael Calosso; Guillaume Tambutet; Daniel Charpentier; Gabrielle St-Pierre; Marc Vaillancourt; Mohammed Bencheqroun; Jean-Philippe Gratton; Michel Prévost; Yvan Guindon
Journal: ACS Med Chem Lett Date: 2014-07-16 Impact factor: 4.345

4. Shaping up for structural glycomics: a predictive protocol for oligosaccharide conformational analysis applied to N-linked glycans.

Authors: Benedict M Sattelle; Andrew Almond
Journal: Carbohydr Res Date: 2013-10-30 Impact factor: 2.104

Preorganization of the Bioactive Conformation of Sialyl Lewis(X) Analogues Correlates with Their Affinity to E-Selectin.

1. GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice.

2. Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow.

3. Acyclic tethers mimicking subunits of polysaccharide ligands: selectin antagonists.

4. Shaping up for structural glycomics: a predictive protocol for oligosaccharide conformational analysis applied to N-linked glycans.

Review 5. Selectins-The Two Dr. Jekyll and Mr. Hyde Faces of Adhesion Molecules-A Review.

Review 6. Bioisosteres of Carbohydrate Functional Groups in Glycomimetic Design.

7. Chemoenzymatic synthesis of functional sialyl Lewis(x) mimetics with a heteroaromatic core.

Review 8. From carbohydrate leads to glycomimetic drugs.