| Literature DB >> 11385492 |
Abstract
The strong allogeneic response to donor MHC molecules in transplantation and the weak response to tumor antigens represent two important and divergent but potentially interactive immune responses. A patient's response to allogeneic MHC molecules might promote an effective T-cell response to self MHC-restricted tumor peptides and the possibilities for this are discussed here. These allogeneic responses might successfully be harnessed to promote the immune eradication of metastatic cancer.Entities:
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Year: 2001 PMID： 11385492 DOI： 10.1038/89008
Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440