Literature DB >> 11384780

Angiotensin and its AT2 receptor: new insights into an old system.

M Stoll1, T Unger.   

Abstract

The AT2 receptor represents a true receptor, but signals and functions in unexpected ways compared to the respective features of the 'classical' AT1 receptor. Moreover, some of the actions of the AT2 receptor are even directly opposed to those of the AT1 receptor, especially concerning the growth- and differentiation-modulating actions of ANG II. The regulation of the AT2 receptor itself by its agonist, as well as by growth factors during ontogenesis, and its acknowledged effects on the regulation of cell growth, differentiation and apoptosis, points towards a role of a program modulator in embryonic development and regeneration.

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Year:  2001        PMID: 11384780     DOI: 10.1016/s0167-0115(01)00246-4

Source DB:  PubMed          Journal:  Regul Pept        ISSN: 0167-0115


  19 in total

1.  Gbeta gamma -independent constitutive association of Galpha s with SHP-1 and angiotensin II receptor AT2 is essential in AT2-mediated ITIM-independent activation of SHP-1.

Authors:  Ying-Hong Feng; Yan Sun; Janice G Douglas
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-09       Impact factor: 11.205

2.  Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.

Authors:  Ana Quenia Gomes da Silva; Marco Antônio Peliky Fontes; Nancy Lapp Kanagy
Journal:  Brain Res       Date:  2010-10-30       Impact factor: 3.252

3.  Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice.

Authors:  Chiyo Doi; Noboru Egashira; Atsushi Kawabata; Dharmendra Kumar Maurya; Naomi Ohta; Deepthi Uppalapati; Rie Ayuzawa; Lara Pickel; Yuka Isayama; Deryl Troyer; Susumu Takekoshi; Masaaki Tamura
Journal:  BMC Cancer       Date:  2010-02-24       Impact factor: 4.430

Review 4.  Microglia mediated neuroinflammation - signaling regulation and therapeutic considerations with special reference to some natural compounds.

Authors:  Yue-Yi Yao; Eng-Ang Ling; Di Lu
Journal:  Histol Histopathol       Date:  2020-07-14       Impact factor: 2.303

5.  Association of polymorphisms in angiotensin II receptor genes with aldosterone-producing adenoma.

Authors:  Jinzhi Ouyang; Zhun Wu; Jinchun Xing; Yongji Yan; Guoxi Zhang; Baojun Wang; Hongzhao Li; Xin Ma; Xu Zhang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2011-06-14

6.  Reduced expression of MTUS1 mRNA is correlated with poor prognosis in bladder cancer.

Authors:  Jun Xiao; Jun-Xing Chen; Yu-Ping Zhu; Lin-Yu Zhou; Qi-An Shu; Ling-Wu Chen
Journal:  Oncol Lett       Date:  2012-04-05       Impact factor: 2.967

Review 7.  The role of angiotensin II in regulating vascular structural and functional changes in hypertension.

Authors:  Rhian M Touyz
Journal:  Curr Hypertens Rep       Date:  2003-04       Impact factor: 5.369

8.  A possible anti-inflammatory role of angiotensin II type 2 receptor in immune-mediated glomerulonephritis during type 1 receptor blockade.

Authors:  Hirokazu Okada; Tsutomu Inoue; Tomohiro Kikuta; Yusuke Watanabe; Yoshihiko Kanno; Shinichi Ban; Takeshi Sugaya; Masatsugu Horiuchi; Hiromichi Suzuki
Journal:  Am J Pathol       Date:  2006-11       Impact factor: 4.307

9.  Adenosine protects against angiotensin II-induced apoptosis in rat cardiocyte cultures.

Authors:  Ilan Goldenberg; Asher Shainberg; Kenneth A Jacobson; Vladimir Shneyvays; Ehud Grossman
Journal:  Mol Cell Biochem       Date:  2003-10       Impact factor: 3.396

10.  Effect of telmisartan on cardiovascular complications associated with streptozotocin diabetic rats.

Authors:  Bhoomika R Goyal; Pravin Mesariya; Ramesh K Goyal; Anita A Mehta
Journal:  Mol Cell Biochem       Date:  2008-04-19       Impact factor: 3.396

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