Literature DB >> 11384742

Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil.

M R Johnson1, R B Diasio.   

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Year:  2001        PMID： 11384742     DOI： 10.1016/s0065-2571(00)00011-x

Source DB:  PubMed          Journal:  Adv Enzyme Regul        ISSN： 0065-2571


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  30 in total

1.  Investigation of IVS14 + 1G > A polymorphism of DPYD gene in a group of Bosnian patients treated with 5-Fluorouracil and capecitabine.

Authors:  Timur Cerić; Nermina Obralić; Lejla Kapur-Pojskić; Drazenka Macić; Semir Beslija; Anes Pasić; Sejla Cerić
Journal:  Bosn J Basic Med Sci       Date:  2010-05       Impact factor: 3.363

2.  TYMS and DPYD polymorphisms in a Turkish population.

Authors:  H S Süzen; N Yüce; G Güvenç; Y Duydu; T Erke
Journal:  Eur J Clin Pharmacol       Date:  2005-11-17       Impact factor: 2.953

3.  Estimating the Effectiveness of DPYD Genotyping in Italian Individuals Suffering from Cancer Based on the Cost of Chemotherapy-Induced Toxicity.

Authors:  Vasileios Fragoulakis; Rossana Roncato; Chiara Dalle Fratte; Fabrizio Ecca; Marina Bartsakoulia; Federico Innocenti; Giuseppe Toffoli; Erika Cecchin; George P Patrinos; Christina Mitropoulou
Journal:  Am J Hum Genet       Date:  2019-05-30       Impact factor: 11.025

4.  microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sites.

Authors:  Steven M Offer; Gabriel L Butterfield; Calvin R Jerde; Croix C Fossum; Natalie J Wegner; Robert B Diasio
Journal:  Mol Cancer Ther       Date:  2014-01-08       Impact factor: 6.261

5.  Unpredicted severe toxicity after 5-fluorouracil treatment due to dihydropyrimidine dehydrogenase deficiency.

Authors:  Jin Ho Baek; Jong Gwang Kim; Shi Nae Kim; Dong Hwan Kim; Sang Kyun Sohn; Young Jun Hong; Kyu Bo Lee
Journal:  Korean J Intern Med       Date:  2006-03       Impact factor: 2.884

6.  Gene-Specific Variant Classifier (DPYD-Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase.

Authors:  Shikshya Shrestha; Cheng Zhang; Calvin R Jerde; Qian Nie; Hu Li; Steven M Offer; Robert B Diasio
Journal:  Clin Pharmacol Ther       Date:  2018-02-02       Impact factor: 6.875

7.  Quantitative Contribution of rs75017182 to Dihydropyrimidine Dehydrogenase mRNA Splicing and Enzyme Activity.

Authors:  Q Nie; S Shrestha; E E Tapper; C S Trogstad-Isaacson; K J Bouchonville; A M Lee; R Wu; C R Jerde; Z Wang; P A Kubica; S M Offer; R B Diasio
Journal:  Clin Pharmacol Ther       Date:  2017-05-26       Impact factor: 6.875

8.  Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity.

Authors:  André B P van Kuilenburg; Judith Meijer; Adri N P M Mul; Rutger Meinsma; Veronika Schmid; Doreen Dobritzsch; Raoul C M Hennekam; Marcel M A M Mannens; Marion Kiechle; Marie-Christine Etienne-Grimaldi; Heinz-Josef Klümpen; Jan Gerard Maring; Veerle A Derleyn; Ed Maartense; Gérard Milano; Raymon Vijzelaar; Eva Gross
Journal:  Hum Genet       Date:  2010-08-29       Impact factor: 4.132

9.  DIHYDROPYRIMIDINE DEHYDROGENASE DEFICIENCY (DPD) IN GI MALIGNANCIES: EXPERIENCE OF 4-YEARS.

Authors:  M Wasif Saif; Kostas Syrigos; Ranee Mehra; Lori K Mattison; Robert B Diasio
Journal:  Pak J Med Sci       Date:  2007       Impact factor: 1.088

10.  Dihydropyrimidine Dehydrogenase Deficiency: Homozygosity for an Extremely Rare Variant in DPYD due to Uniparental Isodisomy of Chromosome 1.

Authors:  André B P van Kuilenburg; Judith Meijer; Rutger Meinsma; Belén Pérez-Dueñas; Marielle Alders; Zahurul A Bhuiyan; Rafael Artuch; Raoul C M Hennekam
Journal:  JIMD Rep       Date:  2018-10-23
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