Literature DB >> 11384741

The protein kinase activity modulation sites: mechanisms for cellular regulation - targets for therapeutic intervention.

R A Engh1, D Bossemeyer.   

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Year:  2001        PMID： 11384741     DOI： 10.1016/s0065-2571(00)00010-8

Source DB:  PubMed          Journal:  Adv Enzyme Regul        ISSN： 0065-2571


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  10 in total

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4.  Affinity reagents that target a specific inactive form of protein kinases.

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Journal:  Chem Biol       Date:  2010-02-26

5.  Allosteric IGF-1R Inhibitors.

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6.  A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

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7.  Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A.

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8.  Activation of protein kinase Calpha by EPAC1 is required for the ERK- and CCAAT/enhancer-binding protein beta-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells.

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9.  Novel benzylidene benzofuranone analogues as potential anticancer agents: design, synthesis and in vitro evaluation based on CDK2 inhibition assays.

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10.  Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2.

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  10 in total

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