Literature DB >> 11383944

Sarcoidosis presenting as an intramedullary spinal cord lesion.

F B Maroun1, F J O'Dea, G Mathieson, G Fox, G Murray, J C Jacob, R Reddy, R Avery.   

Abstract

OBJECTIVES: Sarcoidosis affects the spinal cord in only 0.43% of patients with sarcoidosis. Usually there is systemic involvement prior to the development of cord lesions. We present a case of sarcoid isolated to the intramedullary spinal cord, which was a diagnostic and therapeutic challenge. We review the case and then present a review of the literature with an emphasis on presentation, diagnosis and treatment.
METHODS: We have reviewed a patient who presented with an isolated sarcoid granuloma affecting the cervical spinal cord. All pertinent history and physical information was extracted from the patient's chart and through patient interview. Laboratory, radiographic and pathological investigations are presented. RESULTS AND
CONCLUSIONS: Fourteen patients have been reported with isolated intramedullary spinal cord sarcoidosis. Current practice supports the role of surgery for biopsy; mainstay of treatment is corticosteroids.

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Mesh:

Year:  2001        PMID: 11383944     DOI: 10.1017/s0317167100052884

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN: 0317-1671            Impact factor:   2.104


  6 in total

Review 1.  Sarcoidosis of the spinal cord: literature review and report of eight cases.

Authors:  Samer Saleh; Chandan Saw; Kamel Marzouk; Om Sharma
Journal:  J Natl Med Assoc       Date:  2006-06       Impact factor: 1.798

2.  Intramedullary sarcoidosis presenting with delayed spinal cord swelling after cervical laminoplasty for compressive cervical myelopathy.

Authors:  Du Ho Kwon; Sun-Ho Lee; Eun-Sang Kim; Whan Eoh
Journal:  J Korean Neurosurg Soc       Date:  2014-11-30

3.  Isolated spinal cord neurosarcoidosis diagnosed by cord biopsy and thalidomide trial.

Authors:  Suk-Won Ahn; Kyoung-Tae Kim; Young-Chul Youn; Oh-Sang Kwon; Young-Baeg Kim
Journal:  J Korean Med Sci       Date:  2010-12-22       Impact factor: 2.153

Review 4.  Intramedullary lesions of the conus medullaris: differential diagnosis and surgical management.

Authors:  Florian H Ebner; Florian Roser; Marcus A Acioly; Wolfgang Schoeber; Marcos Tatagiba
Journal:  Neurosurg Rev       Date:  2008-09-27       Impact factor: 3.042

5.  Intramedullary Cervical Sarcoidosis as the Initial Presentation of Systemic Sarcoidosis.

Authors:  Rishi N Razdan; Juan Carlos P Lozada; Shashi Chaddha
Journal:  Radiol Case Rep       Date:  2016-01-05

6.  Isolated spinal neurosarcoidosis: An enigmatic intramedullary spinal cord pathology-case report and review of the literature.

Authors:  Manish K Kasliwal; Aparna Harbhajanka; Sukriti Nag; John E O'Toole
Journal:  J Craniovertebr Junction Spine       Date:  2013-07
  6 in total

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