Literature DB >> 11383782

Favorable outcome after composite valve-graft replacement in patients older than 65 years.

M P Ehrlich1, M A Ergin, J N McCullough, S L Lansman, J D Galla, C A Bodian, R B Griepp.   

Abstract

BACKGROUND: Concomitant surgical replacement of the aortic valve and ascending aorta is an ideal treatment for aortic root aneurysms, but there may be hesitation in its use in older patients, despite their known increased risk of rupture. This study was conducted to examine our results in 84 patients older than 65 years undergoing elective aortic root resection with composite valve-graft replacement.
METHODS: Eighty-four patients older than 65 years were operated on between June 1987 and August 1998. Median age was 74 years (range, 66 to 89 years), and 57 patients were men. Seventeen patients were undergoing reoperation. Aortic insufficiency was present in 70 patients. Forty-seven patients received a conduit using a bioprosthesis, whereas in 37 a mechanical valved conduit (St. Jude) was used. The ascending aorta alone was replaced in 23 patients; 50 had hemi-arch replacement, and in 11 the entire aortic arch was replaced.
RESULTS: Hospital mortality was 8.3% (7 of 84). Sixteen late deaths (19%) were noted during a median follow-up of 3.2 years (range, 0 to 10 years). Only one late death was aorta-related. The incidence of thrombotic or hemorrhagic complications was 2.1/100 patient-years, with equal frequency for both mechanical and bioprosthetic valves.
CONCLUSIONS: We conclude that composite valve-graft replacement in elderly patients results in a low operative mortality, yields excellent long-term survival, and averts fatal aneurysm rupture in this high-risk population.

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Year:  2001        PMID: 11383782     DOI: 10.1016/s0003-4975(01)02405-5

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  5 in total

1.  A systematic review and meta-analysis of mechanical vs biological composite aortic root replacement, early and 1-year results.

Authors:  Mohamad Bashir; Amer Harky; Saied Froghi; Benjamin Adams; Megan Garner; Prity Gupta; Aung Oo; Rakesh Uppal
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-10-10

2.  New use of teflon to reduce bleeding in modified bentall operation.

Authors:  Onur Sokullu; Soner Sanioglu; Gokcen Orhan; M Sinan Kut; Oral Hastaoglu; Pelin Karaca; Batuhan Ozay; Umut Ayoglu; Fuat Bilgen
Journal:  Tex Heart Inst J       Date:  2008

3.  Aortic root surgery in septuagenarians: impact of different surgical techniques.

Authors:  Nawid Khaladj; Rainer Leyh; Malakh Shrestha; Sven Peterss; Axel Haverich; Christian Hagl
Journal:  J Cardiothorac Surg       Date:  2009-04-21       Impact factor: 1.637

4.  A simple modified Bentall technique for surgical reconstruction of the aortic root - short and long term outcomes.

Authors:  Pouya Nezafati; Ali Shomali; Mohammad Hassan Nezafati
Journal:  J Cardiothorac Surg       Date:  2015-10-26       Impact factor: 1.637

5.  Brazilian Single-Center Experience with Aortic Root Replacement in 448 Patients: What Is the Best Technique?

Authors:  Fabrício José Dinato; Ricardo Ribeiro Dias; José Augusto Duncan; Fábio Fernandes; Felix José Alvares Ramirez; Charles Mady; Fabio B Jatene
Journal:  Braz J Cardiovasc Surg       Date:  2020-12-01
  5 in total

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