| Literature DB >> 1138306 |
Abstract
Placental progesterone contents were studied in 10 patients therapeutically aborted at midtrimester by intraamniotic infusions of hypertonic saline, and from 14 patients (12-20 weeks) aborted by intraamniotic instillation of prostaglandin F-2alpha. The mean S.E. of the progesterone was 1.99 plus or minus 0.07 ug/g. placental tissue in the first group, while with prostaglandin abortion the placental progesterone was 1.45 plus or minus 0.08 ug/g. tissue, which is significantly lower than the results in the first group (P equals 0.001). The possible mechanism of action of prostaglandin as an effective abortifacient is discussed.Entities:
Keywords: Abortifacient Agents; Abortion, Drug Induced; Abortion, Induced; Biology; Comparative Studies; Embryo; Endocrine System; Family Planning; Fertility Control, Postconception; Fetal Membranes; Fetus; Hormones; Ingredients And Chemicals; Maternal-fetal Exchange; Physiology; Pregnancy; Pregnancy, Second Trimester; Progestational Hormones; Progesterone--analysis; Prostaglandins--administraction and dosage; Reproduction; Research Methodology; Saline Solution, Hypertonic--administraction and dosage; Studies
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Year: 1975 PMID： 1138306 DOI： 10.1016/0090-6980(75)90156-2
Source DB: PubMed Journal: Prostaglandins ISSN： 0090-6980