Literature DB >> 11382346

Decontamination issues for chemical and biological warfare agents: how clean is clean enough?

E Raber1, A Jin, K Noonan, R McGuire, R D Kirvel.   

Abstract

The objective of this assessment is to determine what level of cleanup will be required to meet regulatory and stakeholder needs in the case of a chemical and/or biological incident at a civilian facility. A literature review for selected, potential chemical and biological warfare agents shows that dose information is often lacking or controversial. Environmental regulatory limits or other industrial health guidelines that could be used to help establish cleanup concentration levels for such agents are generally unavailable or not applicable for a public setting. Although dose information, cleanup criteria, and decontamination protocols all present challenges to effective planning, several decontamination approaches are available. Such approaches should be combined with risk-informed decision making to establish reasonable cleanup goals for protecting health, property, and resources. Key issues during a risk assessment are to determine exactly what constitutes a safety hazard and whether decontamination is necessary or not for a particular scenario. An important conclusion is that cleanup criteria are site dependent and stakeholder specific. The results of a modeling exercise for two outdoor scenarios are presented to reinforce this conclusion. Public perception of risk to health, public acceptance of recommendations based on scientific criteria, political support, time constraints, and economic concerns must all be addressed in the context of a specific scenario to yield effective and acceptable decontamination.

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Year:  2001        PMID: 11382346     DOI: 10.1080/09603120020047519

Source DB:  PubMed          Journal:  Int J Environ Health Res        ISSN: 0960-3123            Impact factor:   3.411


  8 in total

1.  Prehospital management and medical intervention after a chemical attack.

Authors:  L Kenar; T Karayilanoglu
Journal:  Emerg Med J       Date:  2004-01       Impact factor: 2.740

2.  Rapid-viability PCR method for detection of live, virulent Bacillus anthracis in environmental samples.

Authors:  Sonia E Létant; Gloria A Murphy; Teneile M Alfaro; Julie R Avila; Staci R Kane; Ellen Raber; Thomas M Bunt; Sanjiv R Shah
Journal:  Appl Environ Microbiol       Date:  2011-07-15       Impact factor: 4.792

3.  Identification by quantitative carrier test of surrogate spore-forming bacteria to assess sporicidal chemicals for use against Bacillus anthracis.

Authors:  Miles R Majcher; Kathryn A Bernard; Syed A Sattar
Journal:  Appl Environ Microbiol       Date:  2007-12-14       Impact factor: 4.792

4.  Developing Health-Based Pre-Planning Clearance Goals for Airport Remediation Following Chemical Terrorist Attack: Introduction and Key Assessment Considerations.

Authors:  Annetta Watson; Linda Hall; Ellen Raber; Veronique D Hauschild; Fredrick Dolislager; Adam H Love; M Leslie Hanna
Journal:  Hum Ecol Risk Assess       Date:  2011-02-12       Impact factor: 5.190

5.  Design and construction of a low cost air purifier for killing harmful airborne microorganisms using a combination of a strong multi-directional electric-field and an ultra violet light.

Authors:  D N P Ruwan Jayakantha; H M N Bandara; Nadeesha M Gunawardana; R P V Jayantha Rajapakse; Dulari S Thilakarathne; Elisabetta Comini; Nanda Gunawardhana; S M M L Karunarathne
Journal:  HardwareX       Date:  2022-02-11

6.  The Different Sensitive Behaviors of a Hydrogen-Bond Acidic Polymer-Coated SAW Sensor for Chemical Warfare Agents and Their Simulants.

Authors:  Yin Long; Yang Wang; Xiaosong Du; Luhua Cheng; Penglin Wu; Yadong Jiang
Journal:  Sensors (Basel)       Date:  2015-07-28       Impact factor: 3.576

7.  Caenorhabditis elegans Predation on Bacillus anthracis: Decontamination of Spore Contaminated Soil with Germinants and Nematodes.

Authors:  Bettina Schelkle; Young Choi; Leslie W Baillie; William Richter; Fatih Buyuk; Elif Celik; Morgan Wendling; Mitat Sahin; Theresa Gallagher
Journal:  Front Microbiol       Date:  2018-01-05       Impact factor: 5.640

8.  α-Conotoxin Decontamination Protocol Evaluation: What Works and What Doesn't.

Authors:  Matthew W Turner; John R Cort; Owen M McDougal
Journal:  Toxins (Basel)       Date:  2017-09-14       Impact factor: 4.546

  8 in total

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