Literature DB >> 11382135

The origin of life. II: How did it begin?

P Davies1.   

Abstract

The problem of how a mixture of chemicals can spontaneously transform themselves into even a simple living organism remains one of the great outstanding challenges to science. Various primordial soup theories have been proposed in which chemical self-organization brings about the required level of complexity. Major conceptual obstacles remain, however, such as the emergence of the genetic code, and the "chicken-and-egg" problem concerning which came first: nucleic acids or proteins. Currently fashionable is the so-called RNA world theory, which casts RNA in the role of both chicken and egg. Other theories assume that protein chemistry and even clay crystal life came before nucleic acids. To be fully successful, a theory of biogenesis has to explain not merely the emergence of molecular replication and chemical complexity, but the crucial information content and information processing capabilities of the living cell.

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Year:  2001        PMID: 11382135     DOI: 10.3184/003685001783239096

Source DB:  PubMed          Journal:  Sci Prog        ISSN: 0036-8504            Impact factor:   2.774


  2 in total

1.  Prebiotic chemical refugia: multifaceted scenario for the formation of biomolecules in primitive Earth.

Authors:  Francisco Prosdocimi; Sávio Torres de Farias; Marco V José
Journal:  Theory Biosci       Date:  2022-08-30       Impact factor: 1.315

2.  Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences.

Authors:  Julien Derr; Michael L Manapat; Sudha Rajamani; Kevin Leu; Ramon Xulvi-Brunet; Isaac Joseph; Martin A Nowak; Irene A Chen
Journal:  Nucleic Acids Res       Date:  2012-02-07       Impact factor: 16.971

  2 in total

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