Literature DB >> 113821

Interactions between motor activity and sterotypy in cocaine-treated rats.

A K Bhattacharyya, S N Pradhan.   

Abstract

Effect of a single administration of a dose (5, 10, or 15 mg/kg, i.p.) of cocaine hydrochloride on spontaneous motor activity (SMA) and stereotypy (ST), and interactions between these behaviors were investigated in rats. SMA showed peak increases within 10 min and at 120 min after cocaine injection. Drug-induced stereotypy was maximal during the interval between these two peaks in SMA. Several neurotransmitters may be involved in the interactions between SMA and ST.

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Year:  1979        PMID: 113821     DOI: 10.1007/bf00433569

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  2 in total

1.  Correlation of behavioral and neurochemical effects of acute administration of cocaine in rats.

Authors:  S Pradhan; S N Roy; S N Pradhan
Journal:  Life Sci       Date:  1978-05-15       Impact factor: 5.037

2.  Stereotyped activities produced by amphetamine in several animal species and man.

Authors:  A Randrup; I Munkvad
Journal:  Psychopharmacologia       Date:  1967
  2 in total
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4.  Cocaine: effects on acoustic startle and startle elicited electrically from the cochlear nucleus.

Authors:  T P Harty; M Davis
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

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7.  5-HT(2A) receptor blockade and 5-HT(2C) receptor activation interact to reduce cocaine hyperlocomotion and Fos protein expression in the caudate-putamen.

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  8 in total

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