| Literature DB >> 11381257 |
P Sklar1, S G Schwab, N M Williams, M Daly, S Schaffner, W Maier, M Albus, M Trixler, P Eichhammer, B Lerer, J Hallmayer, N Norton, H Williams, S Zammit, A G Cardno, S Jones, G McCarthy, V Milanova, G Kirov, M C O'Donovan, E S Lander, M J Owen, D B Wildenauer.
Abstract
A genetic association between NOTCH4 and schizophrenia has previously been proposed. Unsing all markers previously shown to be associated, we found no evidence for such in three independent family-based samples (n=519 parent-offspring trios), and a case-control sample derived from the same ethnic background as the original observation. These data strongly suggest that NOTCH4 is not a significant susceptibility allele for schizophrenia.Entities:
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Year: 2001 PMID： 11381257 DOI： 10.1038/88836
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330