Literature DB >> 11379169

[Increased consumption of drugs among the elderly results in greater risk of problems].

J Fastbom1.   

Abstract

With aging comes an increasing prevalence of diseases and symptoms that frequently require pharmaceutical treatment. However, aging also brings about bodily changes that result in increased effects and prolonged action of many drugs. Multiple drug use--often termed polypharmacy--seen in many elderly individuals, is the most important risk factor for adverse drug reactions (ADR) and increases the risk of drug interactions and poor compliance. ADR's are responsible for about 10% of all hospital admissions of elderly patients. The drugs most commonly involved are cardiovascular, psychotropics and anti-inflammatory agents. Many of these ADR's are dose-dependent and preventable. Drug use has increased over the last few years, largely thanks to the availability of new and effective agents. This calls for increased vigilance and prudence in prescribing for the elderly.

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Year:  2001        PMID: 11379169

Source DB:  PubMed          Journal:  Lakartidningen        ISSN: 0023-7205


  6 in total

1.  Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems.

Authors:  Kirsten K Viktil; Hege S Blix; Tron A Moger; Aasmund Reikvam
Journal:  Br J Clin Pharmacol       Date:  2006-08-30       Impact factor: 4.335

2.  Dementia management programme in a community setting and the use of psychotropic drugs in the elderly population.

Authors:  Erik Jedenius; Kristina Johnell; Johan Fastbom; Jan Strömqvist; Bengt Winblad; Niels Andreasen
Journal:  Scand J Prim Health Care       Date:  2011-07-11       Impact factor: 2.581

3.  Comorbidity-polypharmacy score: a novel adjunct in post-emergency department trauma triage.

Authors:  Carla F Justiniano; David C Evans; Charles H Cook; Daniel S Eiferman; Anthony T Gerlach; Paul R Beery; David E Lindsey; Gary E A Saum; Claire V Murphy; Sidney F Miller; Thomas J Papadimos; Steven M Steinberg; Stanislaw P A Stawicki
Journal:  J Surg Res       Date:  2012-05-31       Impact factor: 2.192

4.  Pre-injury polypharmacy as a predictor of outcomes in trauma patients.

Authors:  David C Evans; Anthony T Gerlach; Jonathan M Christy; Amy M Jarvis; David E Lindsey; Melissa L Whitmill; Daniel Eiferman; Claire V Murphy; Charles H Cook; Paul R Beery; Steven M Steinberg; Stanislaw Pa Stawicki
Journal:  Int J Crit Illn Inj Sci       Date:  2011-07

5.  Can gender difference in prescription drug use be explained by gender-related morbidity?: a study on a Swedish population during 2006.

Authors:  Jessica Skoog; Patrik Midlöv; Lars Borgquist; Jan Sundquist; Anders Halling
Journal:  BMC Public Health       Date:  2014-04-08       Impact factor: 3.295

6.  Licit prescription drug use in a Swedish population according to age, gender and socioeconomic status after adjusting for level of multi-morbidity.

Authors:  Kristine Thorell; Jessica Skoog; Andrzej Zielinski; Lars Borgquist; Anders Halling
Journal:  BMC Public Health       Date:  2012-07-31       Impact factor: 3.295

  6 in total

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