Literature DB >> 11378374

Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2.

D Dhanak1, L T Christmann, M G Darcy, R M Keenan, S D Knight, J Lee, L H Ridgers, H M Sarau, D H Shah, J R White, L Zhang.   

Abstract

Highly potent CCR3 antagonists have been developed from a previously reported series of phenylalanine ester-based leads. Solution-phase, parallel synthesis optimization was utilized to identify highly potent, functional CCR3 antagonists.

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Year:  2001        PMID： 11378374     DOI： 10.1016/s0960-894x(01)00249-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  G protein-coupled receptors: in silico drug discovery in 3D.

Authors:  Oren M Becker; Yael Marantz; Sharon Shacham; Boaz Inbal; Alexander Heifetz; Ori Kalid; Shay Bar-Haim; Dora Warshaviak; Merav Fichman; Silvia Noiman
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-26       Impact factor: 11.205

Review 2.  G protein-coupled receptors--recent advances.

Authors:  Dorota Latek; Anna Modzelewska; Bartosz Trzaskowski; Krzysztof Palczewski; Sławomir Filipek
Journal:  Acta Biochim Pol       Date:  2012-12-18       Impact factor: 2.149
  2 in total

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