Literature DB >> 11378369

Effect of zinc ion on the inhibition of carboxypeptidase A by imidazole-bearing substrate analogues.

M S Han1, D H Kim.   

Abstract

Competitive inhibitors of carboxypeptidase A, 2-(4-imidazoyl)hydrocinnamic acid (1) and its congeners (2-4) that bear an imidazole ring as the zinc-ligating functionality have been evaluated for their CPA inhibitory activity in the presence of zinc ion to find that the zinc ion augments the inhibitory potency by up to 212-fold.

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Year:  2001        PMID： 11378369     DOI： 10.1016/s0960-894x(01)00226-8

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  2-(1H-Benzimidazol-2-yl)phenol.

Authors:  S M Prakash; A Thiruvalluvar; S Rosepriya; N Srinivasan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-01-22

2.  Experimental and Theoretical Analysis of Metal Complex Diffusion through Cell Monolayer.

Authors:  Katarzyna Gałczyńska; Jarosław Rachuna; Karol Ciepluch; Magdalena Kowalska; Sławomir Wąsik; Tadeusz Kosztołowicz; Katarzyna D Lewandowska; Jacek Semaniak; Krystyna Kurdziel; Michał Arabski
Journal:  Entropy (Basel)       Date:  2021-03-17       Impact factor: 2.524
  2 in total

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