Literature DB >> 11378368

Modification of constrained peptides by ring-closing metathesis reaction.

S Kotha1, N Sreenivasachary, K Mohanraja, S Durani.   

Abstract

Ring-closing metathesis (RCM) with alpha,alpha-diallylglycyl peptides is shown to furnish alpha,alpha-cyclopentenylglycyl peptides as conformationally restrained analogues in the form of post-translational type peptide modification suitable for both peptidomimetic and combinatorial chemistry applications.

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Year:  2001        PMID： 11378368     DOI： 10.1016/s0960-894x(01)00227-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  On the two-component microwave-mediated reaction of isonitriles with carboxylic acids: regarding alleged formimidate carboxylate mixed anhydrides.

Authors:  Xuechen Li; Yu Yuan; William F Berkowitz; Louis J Todaro; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2008-09-11       Impact factor: 15.419

2.  Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps.

Authors:  Ajay Kumar Chinnam; Mukesh Eknathrao Shirbhate; Sambasivarao Kotha
Journal:  Beilstein J Org Chem       Date:  2015-08-31       Impact factor: 2.883

3.  Synthesis of C 3-symmetric star-shaped molecules containing α-amino acids and dipeptides via Negishi coupling as a key step.

Authors:  Sambasivarao Kotha; Saidulu Todeti
Journal:  Beilstein J Org Chem       Date:  2019-02-08       Impact factor: 2.883

4.  One-pot thiol-free synthetic approach to sulfides, and sulfoxides selectively.

Authors:  Sambasivarao Kotha; Naveen Kumar Gupta; Saima Ansari
Journal:  RSC Adv       Date:  2022-09-05       Impact factor: 4.036
  4 in total

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