| Literature DB >> 11377211 |
E V O'Loughlin1, R M Robins-Browne.
Abstract
Shigella dysenteriae and Shiga-toxin-producing Escherichia coli (STEC) elaborate the AB holotoxins, Shiga or Shiga-like toxins (Stx). Stx play a major role in the pathogenesis of haemorrhagic colitis and haemolytic uremic syndrome. This review provides an overview of the mechanisms of action of Stx and a model of the pathogenesis of Stx-induced disease.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11377211 DOI: 10.1016/s1286-4579(01)01405-8
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700