| Literature DB >> 11376799 |
H Zattara-Cannoni1, P Roll, D Figarella-Branger, G Lena, H Dufour, F Grisoli, A M Vagner-Capodano.
Abstract
It is known that, following radiotherapy, secondary cancer may occur after a long latent period. Few cytogenetic studies have been reported on tumors of the central nervous system occurring after radiotherapy. We report the cytogenetic study of six cases of radiation-induced meningiomas. In all cases, we observed the same chromosome abnormality, der(1)(1qter-->1p11::22q12-->22pter). SKY and CGH techniques allowed us to identify the chromosomal abnormalities. We suggest that a gene localized on 1p13 is involved in radiation-induced meningiomas.Entities:
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Year: 2001 PMID： 11376799 DOI： 10.1016/s0165-4608(00)00398-8
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608