| Literature DB >> 11376490 |
S G Babb1, J Barnett, A L Doedens, N Cobb, Q Liu, B C Sorkin, P C Yelick, P A Raymond, J A Marrs.
Abstract
Zebrafish E-cadherin (cdh1) cell adhesion molecule cDNAs were cloned. We investigated spatial and temporal expression of cdh1 during early embryogenesis. Expression was observed in blastomeres, the anterior mesoderm during gastrulation, and developing epithelial structures. In the developing nervous system, cdh1 was detected at the pharyngula stage (24 hpf) in the midbrain-hindbrain boundary (MHB). Developmental regulation of MHB formation involves wnt1 and pax2.1. wnt1 expression preceded cdh1 expression during MHB formation, and cdh1 expression in the MHB was dependent on normal development of this structure. Copyright 2001 Wiley-Liss, Inc.Entities:
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Year: 2001 PMID： 11376490 DOI： 10.1002/dvdy.1132
Source DB: PubMed Journal: Dev Dyn ISSN： 1058-8388 Impact factor: 3.780