| Literature DB >> 11376198 |
K Stiasny1, T C Wetter, J Winkelmann, U Brandenburg, T Penzel, M Rubin, H P Hundemer, W H Oertel, C Trenkwalder.
Abstract
An open follow-up of a controlled study in patients with restless legs syndrome (RLS) shows that the beneficial effect of pergolide on RLS symptoms persists throughout at least 1 year. Twenty-two patients of 28 (78.6%) continued to take pergolide. Polysomnographic measurements showed a persistent improvement of PLM index, PLMS arousal index, total sleep time, and sleep efficiency (p = 0.0001). Side effects, in particular nausea, were common but were well controlled by domperidone in most patients.Entities:
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Year: 2001 PMID： 11376198 DOI： 10.1212/wnl.56.10.1399
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910