| Literature DB >> 11374788 |
M Schmidt1, A K Olejnik, K Stepień, A M Olejnik, W Butowska, W Grajek, J B Warchoł, A Gozdzicka-Józefiak.
Abstract
Human papillomavirus type 16 (HPV16) is a major agent in cervical cancer etiology. Its early proteins are responsible for virus persistence, replication and initiation of neoplastic disease. In the present study we describe a use of baculovirus-insect cell expression system for production and study of HPV16 E2 and E4 proteins. The E2 protein binds specifically to viral DNA and E4 protein shows characteristic cytopathic effects on cells.Entities:
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Year: 2001 PMID： 11374788
Source DB: PubMed Journal: Folia Histochem Cytobiol ISSN： 0239-8508 Impact factor: 1.698