Literature DB >> 1137387

Bactericidal activity of combinations of gentamicin with penicillin or clindamycin against Streptococcus mutans.

R J Snyder, C J Wilkowske, J A Washington.   

Abstract

Data derived from testing the bactericidal activity of combinations of penicillin with gentamicin or streptomycin and of clindamycin with gentamicin on nine isolates of Streptococcus mutans were analyzed by preparing isobolograms to determine the presence of additive, synergistic, or antagonistic effects. Synergy with penicillin-aminoglycoside combinations was found in two strains; additive effects occurred in seven instances with penicillin-gentamicin combinations; and antagonism occurred in eight instances with clindamycin-gentamicin combinations.

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Year:  1975        PMID： 1137387      PMCID： PMC429135          DOI： 10.1128/AAC.7.3.333

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  The problem of synergism and antagonism of combined drugs.

Authors:  S LOEWE
Journal:  Arzneimittelforschung       Date:  1953-06

2.  Penicillin-aminoglycoside synergy in experimental Streptococcus viridans endocarditis.

Authors:  M A Sande; R G Irvin
Journal:  J Infect Dis       Date:  1974-05       Impact factor: 5.226

3.  Streptococcus mutans endocarditis.

Authors:  E J Harder; C J Wilkowske; J A Washington; J E Geraci
Journal:  Ann Intern Med       Date:  1974-03       Impact factor: 25.391

4.  Penicillin-sensitive streptococcal endocarditis. In-vitro and clinical observations on penicillin-streptomycin therapy.

Authors:  J C Wolfe; W D Johnson
Journal:  Ann Intern Med       Date:  1974-08       Impact factor: 25.391
  4 in total
  4 in total

1.  Bactericidal activity of combinations of penicillin or clindamycin with gentamicin or streptomycin against species of viridans streptococci.

Authors:  R Duperval; N J Bill; J E Geraci; J A Washington
Journal:  Antimicrob Agents Chemother       Date:  1975-12       Impact factor: 5.191

2.  Bactericidal activity of the combinations of gentamicin with clindamycin or chloramphenicol against species of Escherichia coli and Bacteroides fragilis.

Authors:  J Klastersky; M Husson
Journal:  Antimicrob Agents Chemother       Date:  1977-08       Impact factor: 5.191

3.  AZDAST the new horizon in antimicrobial synergism detection.

Authors:  Navid Ziaei-Darounkalaei; Mehrdad Ameri; Taghi Zahraei-Salehi; Omid Ziaei-Darounkalaei; Tahereh Mohajer-Tabrizi; Lotfollah Bornaei
Journal:  MethodsX       Date:  2016-01-07

4.  Inhibition of Streptococcus mutans biofilms with bacterial-derived outer membrane vesicles.

Authors:  Yihui Wang; Joseph P Hoffmann; Sarah M Baker; Kerstin Höner Zu Bentrup; William C Wimley; Joseph A Fuselier; Jacob P Bitoun; Lisa A Morici
Journal:  BMC Microbiol       Date:  2021-08-24       Impact factor: 3.605
  4 in total

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