Literature DB >> 11372732

Effect of granulocyte colony-stimulating factor on chemotherapeutic activity of cytosine arabinoside in acute leukemic cell lines.

K E Cha1, S Y Yoon, K N Lee.   

Abstract

Recent studies have shown the presence of receptors for granulocyte colony-stimulating factor (G-CSF) on lymphoid leukemic cells. To determine the effect of G-CSF on chemotherapeutic activity of cytosine arabinoside (Ara-C) on lymphoid as well as myeloid leukemic cells, we evaluated cell counts, apoptosis, and growth inhibition in HL-60, KG-1, Molt-4, Jijoye, and CCRF-CEM cell lines after incubation with Ara-C (0.1 and 1 micromol/L) and/or 5 ng/mL G-CSE G-CSF potentiated the effect of Ara-C on 2 of 3 lymphoid leukemic cell lines (Molt-4 and Jijoye), whereas it decreased the apoptosis and the effect of Ara-C on myeloid cell lines (HL-60 and KG-1).

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Year:  2001        PMID： 11372732     DOI： 10.1007/bf02981938

Source DB:  PubMed          Journal:  Int J Hematol        ISSN： 0925-5710            Impact factor:   2.490


  32 in total

Review 1.  Granulocyte colony-stimulating factor receptor at various differentiation stages of normal and leukemic hematopoietic cells.

Authors:  K Shinjo; A Takeshita; K Ohnishi; R Ohno
Journal:  Leuk Lymphoma       Date:  1997-03

Review 2.  Granulocyte colony-stimulating factor and its receptor.

Authors:  G D Demetri; J D Griffin
Journal:  Blood       Date:  1991-12-01       Impact factor: 22.113

Review 3.  The granulocyte colony-stimulating factor (G-CSF)/G-CSF receptor (G-CSFR) system in B-cell chronic lymphocytic leukemia.

Authors:  A Corcione; P Tasso; V Pistoia
Journal:  Leuk Lymphoma       Date:  1997-10

4.  Immunogenotypes and clonal culture analysis in B-precursor acute lymphoblastic leukemia.

Authors:  J H Ohyashiki; K Ohyashiki; J Miyauchi; H Fujieda; T Tauchi; M Saito; S Nakazawa; N Kimura; S C Clark; K Toyama
Journal:  Leukemia       Date:  1992-04       Impact factor: 11.528

5.  Granulocyte-colony stimulating factor induces differentiation and apoptosis of CD2, CD7 positive hybrid leukemia cells in vivo and ex vivo.

Authors:  H Fujiwara; N Arima; K Matsushita; S Hidaka; H Ohtsubo; J Fukumori; K Arimura; T Kukita; H Tanaka
Journal:  Leuk Res       Date:  1997-08       Impact factor: 3.156

6.  Leukemic cells with 11q23 translocations express granulocyte colony-stimulating factor (G-CSF) receptor and their proliferation is stimulated with G-CSF.

Authors:  T Inukai; K Sugita; K Iijima; K Goi; T Tezuka; S Kojika; K Kagami; T Mori; A Kinoshita; T Suzuki; T O-Koyama; S Nakazawa
Journal:  Leukemia       Date:  1998-03       Impact factor: 11.528

7.  Frequent gene expression of granulocyte colony-stimulating factor (G-CSF) receptor in CD7+ surface CD3- acute lymphoblastic leukaemia.

Authors:  K Kita; K Nishii; K Ohishi; N Morita; N Takakura; K Kawakami; H Miwa; S Shirakawa
Journal:  Leukemia       Date:  1993-08       Impact factor: 11.528

8.  Enhanced chemosensitivity of clonogenic blasts from patients with acute myeloid leukemia by G-CSF, IL-3 or GM-CSF stimulation.

Authors:  P A te Boekhorst; B Löwenberg; M Vlastuin; P Sonneveld
Journal:  Leukemia       Date:  1993-08       Impact factor: 11.528

9.  A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry.

Authors:  I Schmid; C H Uittenbogaart; B Keld; J V Giorgi
Journal:  J Immunol Methods       Date:  1994-04-15       Impact factor: 2.303

10.  Fludarabine + Ara-C + G-CSF: cytotoxic effect and induction of apoptosis on fresh acute myeloid leukemia cells.

Authors:  P Tosi; G Visani; E Ottaviani; S Manfori; P L Zinzani; S Tura
Journal:  Leukemia       Date:  1994-12       Impact factor: 11.528
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