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Literature DB >> 11369508

Actin is oxidized during myocardial ischemia.

Abstract

Exposure of isolated rat hearts to 30 min global ischemia followed by 60 min reperfusion resulted in a significant 80% increase (p <.05) in actin content of carbonyl groups, which was associated with significant depression (p <.05) of postischemic contractile function. This result supports the hypothesis that one mechanism of postischemic contractile dysfunction may be oxidation of contractile proteins.

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Year: 2001 PMID： 11369508 DOI： 10.1016/s0891-5849(01)00514-7

Source DB: PubMed Journal: Free Radic Biol Med ISSN： 0891-5849 Impact factor: 7.376

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Cited

21 in total

1. Effect of myocardial stunning on thiol status, myofibrillar ATPase and troponin I proteolysis.

Authors: Peter Kaplan; Milena Matejovicová; Ján Lehotsky; Willem Flameng
Journal: Mol Cell Biochem Date: 2002-04 Impact factor: 3.396

2. Accumulation of oxidized proteins in Herpesvirus infected cells.

Authors: Shomita S Mathew; Patrick W Bryant; April D Burch
Journal: Free Radic Biol Med Date: 2010-05-02 Impact factor: 7.376

Review 3. The ubiquitin-proteasome system and cardiovascular disease.

Authors: Saul R Powell; Joerg Herrmann; Amir Lerman; Cam Patterson; Xuejun Wang
Journal: Prog Mol Biol Transl Sci Date: 2012 Impact factor: 3.622

Review 4. The ubiquitin-proteasome system in myocardial ischaemia and preconditioning.

Authors: Saul R Powell; Andras Divald
Journal: Cardiovasc Res Date: 2009-09-30 Impact factor: 10.787

5. Sphingomyelinase depresses force and calcium sensitivity of the contractile apparatus in mouse diaphragm muscle fibers.

Authors: Leonardo F Ferreira; Jennifer S Moylan; Shawn Stasko; Jeffrey D Smith; Kenneth S Campbell; Michael B Reid
Journal: J Appl Physiol (1985) Date: 2012-02-23

Actin is oxidized during myocardial ischemia.

1. Effect of myocardial stunning on thiol status, myofibrillar ATPase and troponin I proteolysis.

2. Accumulation of oxidized proteins in Herpesvirus infected cells.

Review 3. The ubiquitin-proteasome system and cardiovascular disease.

Review 4. The ubiquitin-proteasome system in myocardial ischaemia and preconditioning.

5. Sphingomyelinase depresses force and calcium sensitivity of the contractile apparatus in mouse diaphragm muscle fibers.

Review 6. Proteasome functional insufficiency in cardiac pathogenesis.

7. Tyrosine nitration of mitochondrial proteins during myocardial ischemia and reperfusion.

Review 8. Cysteine oxidative posttranslational modifications: emerging regulation in the cardiovascular system.

Review 9. The ubiquitin proteasome system and myocardial ischemia.

Review 10. The ubiquitin proteasome system in human cardiomyopathies and heart failure.