| Literature DB >> 11369260 |
S O Olofsson1, P Stillemark-Billton, L Asp.
Abstract
The assembly of very low-density lipoproteins (VLDL) occurs in two major steps. The first step is the co-and post-translational lipidation of apoB, forming pre-VLDL in the rough endoplasmic reticulum. The microsomal triglyceride transfer protein catalyzes this step. In the second step pre-VLDL is converted to bona fide VLDL in a smooth membrane compartment. This step depends on ADP-ribosylation factor 1 and its activation of phospholipase D.Entities:
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Year: 2000 PMID: 11369260 DOI: 10.1016/s1050-1738(01)00071-8
Source DB: PubMed Journal: Trends Cardiovasc Med ISSN: 1050-1738 Impact factor: 6.677