Literature DB >> 11369250

DNA replication: building the perfect switch.

J F Diffley1.   

Abstract

A sophisticated molecular switch ensures that replication origins are activated just once in each cell cycle. Recent work reveals how the proteolysis of a key replication inhibitor, geminin, by the anaphase promoting complex/cyclosome is an important component of this switch.

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Year:  2001        PMID: 11369250     DOI: 10.1016/s0960-9822(01)00196-8

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  39 in total

1.  Functional analysis of mutant and wild-type Drosophila origin recognition complex.

Authors:  I Chesnokov; D Remus; M Botchan
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-02       Impact factor: 11.205

Review 2.  Making sense of eukaryotic DNA replication origins.

Authors:  D M Gilbert
Journal:  Science       Date:  2001-10-05       Impact factor: 47.728

3.  Functional domains involved in the interaction between Orc1 and transcriptional repressor AlF-C that bind to an origin/promoter of the rat aldolase B gene.

Authors:  Yasushi Saitoh; Satoru Miyagi; Hiroyoshi Ariga; Ken-ichi Tsutsumi
Journal:  Nucleic Acids Res       Date:  2002-12-01       Impact factor: 16.971

4.  Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila.

Authors:  Marito Araki; Robin P Wharton; Zhanyun Tang; Hongtao Yu; Maki Asano
Journal:  EMBO J       Date:  2003-11-17       Impact factor: 11.598

5.  ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase.

Authors:  Kenji Shimada; Philippe Pasero; Susan M Gasser
Journal:  Genes Dev       Date:  2002-12-15       Impact factor: 11.361

6.  Multiple ORC-binding sites are required for efficient MCM loading and origin firing in fission yeast.

Authors:  Tatsuro Takahashi; Eri Ohara; Hideo Nishitani; Hisao Masukata
Journal:  EMBO J       Date:  2003-02-17       Impact factor: 11.598

7.  Biochemical characterization of Cdc6/Orc1 binding to the replication origin of the euryarchaeon Methanothermobacter thermoautotrophicus.

Authors:  Stephanie A Capaldi; James M Berger
Journal:  Nucleic Acids Res       Date:  2004-09-09       Impact factor: 16.971

8.  Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.

Authors:  Emily E Arias; Johannes C Walter
Journal:  Genes Dev       Date:  2004-12-14       Impact factor: 11.361

9.  Studies of the properties of human origin recognition complex and its Walker A motif mutants.

Authors:  Jennifer Giordano-Coltart; Carol Y Ying; Jean Gautier; Jerard Hurwitz
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-23       Impact factor: 11.205

10.  Expression of geminin as a marker of cell proliferation in normal tissues and malignancies.

Authors:  James A Wohlschlegel; Jeffery L Kutok; Andrew P Weng; Anindya Dutta
Journal:  Am J Pathol       Date:  2002-07       Impact factor: 4.307

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