Literature DB >> 11369243

Ras effectors: buying shares in Ras plc.

P J Cullen1.   

Abstract

The debate over whether activated Ras can regulate phosphoinositide-specific phospholipase C (PLC) has been contentious and at times heated. The argument may be resolved by the recent identification of a novel Ras-regulated PLC, but some unexpected properties of this protein are sure to stimulate further controversy.

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Year:  2001        PMID： 11369243     DOI： 10.1016/s0960-9822(01)00189-0

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  7 in total

1.  New insights into the families of PLC enzymes: looking back and going forward.

Authors:  Matilda Katan
Journal:  Biochem J       Date:  2005-11-01       Impact factor: 3.857

2.  Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops.

Authors:  Anatoly Kiyatkin; Edita Aksamitiene; Nick I Markevich; Nikolay M Borisov; Jan B Hoek; Boris N Kholodenko
Journal:  J Biol Chem       Date:  2006-05-09       Impact factor: 5.157

3.  Ral is both necessary and sufficient for the inhibition of myeloid differentiation mediated by Ras.

Authors:  Nader Omidvar; Lorna Pearn; Alan K Burnett; Richard L Darley
Journal:  Mol Cell Biol       Date:  2006-05       Impact factor: 4.272

4.  Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38.

Authors:  Janice C Wolfman; Todd Palmby; Channing J Der; Alan Wolfman
Journal:  Mol Cell Biol       Date:  2002-03       Impact factor: 4.272

Review 5.  Distinct requirements for Ras oncogenesis in human versus mouse cells.

Authors:  Nesrin M Hamad; Joel H Elconin; Antoine E Karnoub; Wenli Bai; Jeremy N Rich; Robert T Abraham; Channing J Der; Christopher M Counter
Journal:  Genes Dev       Date:  2002-08-15       Impact factor: 11.361

6.  PLCε promotes urinary bladder cancer cells proliferation through STAT3/LDHA pathway‑mediated glycolysis.

Authors:  Honglin Cheng; Yanni Hao; Yingying Gao; Yunfeng He; Chunli Luo; Wei Sun; Mengjuan Yuan; Xiaohou Wu
Journal:  Oncol Rep       Date:  2019-03-13       Impact factor: 3.906

Review 7.  The effects of mutant Ras proteins on the cell signalome.

Authors:  Tamás Takács; Gyöngyi Kudlik; Anita Kurilla; Bálint Szeder; László Buday; Virag Vas
Journal:  Cancer Metastasis Rev       Date:  2020-12       Impact factor: 9.264
  7 in total

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