OBJECTIVE: To study the therapeutical mechanism of Feiyan Chuansou Oral Liquid (FCOL) in treating infantile acute respiratory trct infection. METHODS: Clinical and experimental studies with FCOL in treating infantile acute respiratory tract infection. RESULTS: The clinical result showed that the antitussive, expectorant, anti-asthmatic effect and resolution of dry and moist rale and wheezing of FCOL were significantly better in treatment group than those in the control group (P < 0.05). Animal experimental results also showed that antitussive, expectorant, anti-asthmatic effect of FCOL were significantly better than those of the control group (P < 0.05-0.001). Bacteriostatic test in vitro showed that FCOL could inhibit streptococcus pneumoniae, klebsiella pneumoniae, influenza bacilli and staphylococcus aureus. Antivirologic test showed that FCOL could inhibit completely the influenza A virus and respiratory syncytial virus. CONCLUSION:FCOL is an effective preparation in treating infantile acute respiratory infection.
RCT Entities:
OBJECTIVE: To study the therapeutical mechanism of Feiyan Chuansou Oral Liquid (FCOL) in treating infantile acute respiratory trct infection. METHODS: Clinical and experimental studies with FCOL in treating infantile acute respiratory tract infection. RESULTS: The clinical result showed that the antitussive, expectorant, anti-asthmatic effect and resolution of dry and moist rale and wheezing of FCOL were significantly better in treatment group than those in the control group (P < 0.05). Animal experimental results also showed that antitussive, expectorant, anti-asthmatic effect of FCOL were significantly better than those of the control group (P < 0.05-0.001). Bacteriostatic test in vitro showed that FCOL could inhibit streptococcus pneumoniae, klebsiella pneumoniae, influenza bacilli and staphylococcus aureus. Antivirologic test showed that FCOL could inhibit completely the influenza A virus and respiratory syncytial virus. CONCLUSION:FCOL is an effective preparation in treating infantile acute respiratory infection.