Screening and treatment of sexually transmitted diseases: an important strategy for reducing the risk of HIV transmission.

The role of sexually transmitted diseases (STDs) in the spread of human immunodeficiency virus (HIV) infection is reviewed. The rationale for and approach to reducing STD prevalence in high-risk communities are presented. Given the asymptomatic nature of these infections and problems associated with delivering curative therapy, effective interventions will require the use of diagnostic tests for screening and the use of single-dose therapies in appropriate settings: Treatment of individuals with STDs will likely reduce individual risk, while reduction of STD prevalence in high-risk communities may curtail the epidemic spread of HIV.