Literature DB >> 1136078

Ultrastructural characteristics of "aging" of human prostate cells in monolayer cell culture.

B Brehmer, P O Madsen, J M Bloodworth.   

Abstract

Monolayer tissue culture cells from benign nodular hyperplasia of the prostate transferred at 1-2 weeks intervals were examined under the electron microscope after the 3rd, 9th, and 10th transfers. Changes seen after 9 to 10 transfers were interpreted as an "aging process" and consisted of the presence of lysosomes of various types and variations in the mitochondria profile. These changes were described in detail and illustrated and compared to the ultrastructural appearance of monolayer cell cultures in the early transfer stage.

Entities:  

Mesh：

Year:  1975        PMID： 1136078     DOI： 10.1007/bf00256191

Source DB:  PubMed          Journal:  Urol Res        ISSN： 0300-5623


  10 in total

1.  LONG-TERM CULTIVATION OF DIPLOID RAT CELLS.

Authors:  G PETURSSON; J I COUGHLIN; C MEYLAN
Journal:  Exp Cell Res       Date:  1964-01       Impact factor: 3.905

2.  The serial cultivation of human diploid cell strains.

Authors:  L HAYFLICK; P S MOORHEAD
Journal:  Exp Cell Res       Date:  1961-12       Impact factor: 3.905

3.  Comparative ultrastructure of chick fibroblasts in vitro at early and late stages during their growth span.

Authors:  M A Brock; R J Hay
Journal:  J Ultrastruct Res       Date:  1971-08

4.  Growth and hormonal response of cells derived from carcinoma and hyperplasia of the prostate in monolayer cell culture. A possible in vitro model for clinical chemotherapy.

Authors:  B Brehmer; H Marquardt; P O Madsen
Journal:  J Urol       Date:  1972-12       Impact factor: 7.450

5.  Electron microscopic appearance of cells from carcinoma of the prostate in monolayer tissue culture.

Authors:  B Brehmer; J F Riemann; J M Bloodworth; P O Madsen
Journal:  Urol Res       Date:  1973-01

6.  Cytoplasmic components in hepatic cell lysosomes.

Authors:  T P ASHFORD; K R PORTER
Journal:  J Cell Biol       Date:  1962-01       Impact factor: 10.539

7.  A simplified chemostat for the growth of mammalian cells: characteristics of cell growth in continuous culture.

Authors:  E P COHEN; H EAGLE
Journal:  J Exp Med       Date:  1961-02-01       Impact factor: 14.307

8.  STUDIES ON THE INTRACELLULAR DIGESTIVE PROCESS IN MAMMALIAN TISSUE CULTURE CELLS.

Authors:  G B Gordon; L R Miller; K G Bensch
Journal:  J Cell Biol       Date:  1965-05-01       Impact factor: 10.539

9.  Clonal growth in vitro of human cells with fibroblastic morphology; comparison of growth and genetic characteristics of single epithelioid and fibroblast-like cells from a variety of human organs.

Authors:  T T PUCK; S J CIECIURA; H W FISHER
Journal:  J Exp Med       Date:  1957-07-01       Impact factor: 14.307

10.  DEMONSTRATION OF ACID PHOSPHATASE-CONTAINING GRANULES AND CYTOPLASMIC BODIES IN THE EPITHELIUM OF FOETAL RAT DUODENUM DURING CERTAIN STAGES OF DIFFERENTIATION.

Authors:  O BEHNKE
Journal:  J Cell Biol       Date:  1963-08       Impact factor: 10.539
  10 in total

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