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Literature DB >> 11360222

Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome.

P Abboud¹, V Lemée, G Gargala, P Brasseur, J J Ballet, F Borsa-Lebas, F Caron, L Favennec.

Abstract

A case of metronidazole- and albendazole-resistant giardiasis in a patient with the acquired immunodeficiency syndrome was successfully treated with nitazoxanide (1.5 g twice a day for 30 days). Animal studies and in vitro assays showed that the isolate was resistant to both metronidazole and albendazole and susceptible to nitazoxanide.

Entities: Chemical Disease Species

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Year: 2001 PMID： 11360222 DOI： 10.1086/320751

Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079

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Cited

16 in total

Review 1. Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites.

Authors: Vahab Ali; Tomoyoshi Nozaki
Journal: Clin Microbiol Rev Date: 2007-01 Impact factor: 26.132

2. The in vitro anti-giardial activity of extracts from plants that are used for self-medication by AIDS patients in southern Thailand.

Authors: N Sawangjaroen; S Subhadhirasakul; S Phongpaichit; C Siripanth; K Jamjaroen; K Sawangjaroen
Journal: Parasitol Res Date: 2004-11-18 Impact factor: 2.289

Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome.

Review 1. Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites.

2. The in vitro anti-giardial activity of extracts from plants that are used for self-medication by AIDS patients in southern Thailand.

3. Short course combination therapy for giardiasis after nitroimidazole failure.

Review 4. Understanding drug resistance in human intestinal protozoa.

5. Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis.

6. In vitro parasiticidal effect of Nitazoxanide against Echinococcus multilocularis metacestodes.

7. Treatment of giardiasis: current status and future directions.

8. Nitazoxanide in the Treatment of Intestinal Parasitic Infections in Children: A Systematic Review and Meta-Analysis.

Review 9. Current treatment options for Dientamoeba fragilis infections.

10. Incidental Diagnosis of Duodenal Giardiasis.