Literature DB >> 11359592

Postoperative epidural analgesia with bupivacaine and fentanyl: hourly pain assessment in 348 paediatric cases.

C Lejus1, M Surbled, D Schwoerer, M Renaudin, C Guillaud, L Berard, M Pinaud.   

Abstract

BACKGROUND: The objective of this prospective study was the evaluation of the analgesia provided by an epidural infusion of bupivacaine and fentanyl after different types of surgery in children.
METHODS: Data were collected from 348 epidural analgesia in 87 children below 2 years of age, in 80 children between 2 and 6 years and 181 above 6 years of age, for a median duration of 43 postoperative hours. Bupivacaine (mean concentration 0.185%) and fentanyl (5 microg.kg-1.day-1) were administered on the surgical ward.
RESULTS: Pain control was considered excellent in 86% of the 11 072 pain hourly assessments. Analgesia was found to be better for children older than 2 years, and the overall quality of their night's sleep was better than that of older children. Higher pain scores were noted for Nissen fundoplication surgery and club foot repairs. Early discontinuation rarely occurred, and only because of technical problems with the epidural catheter (4%) or insufficient analgesia (6%). Complications were minor (nausea/vomiting 14%, pruritus 0.6%, urinary retention 17%) and easily reversed.
CONCLUSIONS: This combination of bupivacaine-fentanyl provides safe analgesia after major surgery in children with frequent clinical monitoring. Regular pain assessments of intensity and duration are useful to improve the quality of postoperative analgesia.

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Year:  2001        PMID: 11359592     DOI: 10.1046/j.1460-9592.2001.00659.x

Source DB:  PubMed          Journal:  Paediatr Anaesth        ISSN: 1155-5645            Impact factor:   2.556


  3 in total

Review 1.  Neuraxial analgesia in neonates and infants: a review of clinical and preclinical strategies for the development of safety and efficacy data.

Authors:  Suellen M Walker; Tony L Yaksh
Journal:  Anesth Analg       Date:  2012-07-13       Impact factor: 5.108

2.  Ropivacaine has no advantage over bupivacaine in thoracic epidural analgesia for patients with pectus excavatum undergoing the Nuss procedure - a single blind randomized clinical trial comparing efficacy and safety.

Authors:  Małgorzata Walaszczyk; Rafał Wiench; Maja Copik; Jacek Karpe; Małgorzata Łowicka; Anna Pióro; Piotr Knapik; Hanna Misiołek
Journal:  Kardiochir Torakochirurgia Pol       Date:  2018-03-28

3.  Erector spinae plane block for pediatric hip surgery -a case report.

Authors:  Abdelghafour Elkoundi; Aziza Bentalha; Salma Ech-Cherif El Kettani; Ahlam Mosadik; Alae El Koraichi
Journal:  Korean J Anesthesiol       Date:  2018-08-24
  3 in total

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