Literature DB >> 11356950

Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?

B R Dix1, S J Edwards, A W Braithwaite.   

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Year:  2001        PMID： 11356950      PMCID： PMC114255          DOI： 10.1128/JVI.75.12.5443-5447.2001

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


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  63 in total

1.  p53/E1b58kDa complex regulates adenovirus replication.

Authors:  P J Ridgway; A R Hall; C J Myers; A W Braithwaite
Journal:  Virology       Date:  1997-10-27       Impact factor: 3.616

2.  The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle.

Authors:  F D Goodrum; D A Ornelles
Journal:  J Virol       Date:  1997-01       Impact factor: 5.103

3.  ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents.

Authors:  C Heise; A Sampson-Johannes; A Williams; F McCormick; D D Von Hoff; D H Kirn
Journal:  Nat Med       Date:  1997-06       Impact factor: 53.440

Review 4.  Cell cycle targets of the DNA tumor viruses.

Authors:  J R Nevins
Journal:  Curr Opin Genet Dev       Date:  1994-02       Impact factor: 5.578

5.  Control of p53 expression by adenovirus 12 early region 1A and early region 1B 54K proteins.

Authors:  R J Grand; D Owen; S M Rookes; P H Gallimore
Journal:  Virology       Date:  1996-04-01       Impact factor: 3.616

6.  Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells.

Authors:  S K Chiou; C C Tseng; L Rao; E White
Journal:  J Virol       Date:  1994-10       Impact factor: 5.103

7.  Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and DeltaE1B adenovirus replication in human cells.

Authors:  W T Steegenga; N Riteco; J L Bos
Journal:  Oncogene       Date:  1999-09-09       Impact factor: 9.867

8.  HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses.

Authors:  R P Tomko; R Xu; L Philipson
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205

9.  An adenovirus mutant that replicates selectively in p53-deficient human tumor cells.

Authors:  J R Bischoff; D H Kirn; A Williams; C Heise; S Horn; M Muna; L Ng; J A Nye; A Sampson-Johannes; A Fattaey; F McCormick
Journal:  Science       Date:  1996-10-18       Impact factor: 47.728

10.  The transforming oncoproteins determine the mechanism by which p53 suppresses cell transformation: pRb-mediated growth arrest or apoptosis.

Authors:  R Hansen; R Reddel; A Braithwaite
Journal:  Oncogene       Date:  1995-12-21       Impact factor: 9.867
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  16 in total

1.  Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.

Authors:  Sara J Edwards; Brett R Dix; Colleen J Myers; Deirdre Dobson-Le; Lily Huschtscha; Merilyn Hibma; Janice Royds; Antony W Braithwaite
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

2.  E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection.

Authors:  Urs Hobom; Matthias Dobbelstein
Journal:  J Virol       Date:  2004-07       Impact factor: 5.103

3.  Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblasts.

Authors:  Ramon Gonzalez; Wenying Huang; Renee Finnen; Courtney Bragg; S J Flint
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

4.  Complete eradication of xenograft hepatoma by oncolytic adenovirus ZD55 harboring TRAIL-IETD-Smac gene with broad antitumor effect.

Authors:  Shi-Bing Wang; Yuan Tan; Wen Lei; Yi-Gang Wang; Xiu-Mei Zhou; Xiao-Yuan Jia; Kang-Jian Zhang; Liang Chu; Xin-Yuan Liu; Wen-Bin Qian
Journal:  Hum Gene Ther       Date:  2012-07-20       Impact factor: 5.695

5.  Sodium iodide symporter SPECT imaging of a patient treated with oncolytic adenovirus Ad5/3-Δ24-hNIS.

Authors:  Maria Rajecki; Aki Kangasmäki; Leena Laasonen; Sophie Escutenaire; Tanja Hakkarainen; Jarmo Haukka; Ari Ristimäki; Kalevi Kairemo; Lotta Kangasniemi; Timo Kiljunen; Timo Joensuu; Sari Pesonen; Akseli Hemminki
Journal:  Mol Ther       Date:  2011-04       Impact factor: 11.454

Review 6.  Adenoviral vectors for prodrug activation-based gene therapy for cancer.

Authors:  Joshua C Doloff; David J Waxman
Journal:  Anticancer Agents Med Chem       Date:  2014-01       Impact factor: 2.505

Review 7.  [The use of p53 as a tool for human cancer therapy].

Authors:  V P Almazov; D V Kochetkov; P M Chumakov
Journal:  Mol Biol (Mosk)       Date:  2007 Nov-Dec

8.  Human telomerase reverse transcriptase promoter-driven oncolytic adenovirus with E1B-19 kDa and E1B-55 kDa gene deletions.

Authors:  Joshua C Doloff; David J Waxman; Youssef Jounaidi
Journal:  Hum Gene Ther       Date:  2008-12       Impact factor: 5.695

9.  Adenoviral vector-based strategies for cancer therapy.

Authors:  Anurag Sharma; Manish Tandon; Dinesh S Bangari; Suresh K Mittal
Journal:  Curr Drug ther       Date:  2009-05-01

10.  Molecular basis for viral selective replication in cancer cells: activation of CDK2 by adenovirus-induced cyclin E.

Authors:  Pei-Hsin Cheng; Xiao-Mei Rao; Kelly M McMasters; Heshan Sam Zhou
Journal:  PLoS One       Date:  2013-02-20       Impact factor: 3.240
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