Literature DB >> 11356443

Systemic lupus erythematosus in migrants from west Africa compared with Afro-Caribbean people in the UK.

M Molokhia1, P M McKeigue, M Cuadrado, G Hughes.   

Abstract

SLE has a high prevalence in Afro-Caribbean populations but has been reported to be rare in west Africa. We assessed prevalence (per 100000) of SLE in women in an area of south London and estimated it to be 177 (95% CI 135-220) in Afro-Caribbeans, 110 (58-163) in west Africans, and 35 (26-43) in Europeans. The high prevalence of SLE in recent migrants from west Africa suggests that the disease is not rare in west Africa, and that there is a genetic basis for the high risk of SLE in people of west African descent compared with other groups.

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Year:  2001        PMID: 11356443     DOI: 10.1016/S0140-6736(00)04580-3

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  20 in total

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Review 5.  The global burden of SLE: prevalence, health disparities and socioeconomic impact.

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10.  Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population.

Authors:  M Molokhia; C Hoggart; A L Patrick; M Shriver; E Parra; J Ye; A J Silman; P M McKeigue
Journal:  Hum Genet       Date:  2003-01-24       Impact factor: 4.132

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